Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ETT73_RS05570 Genome accession   NZ_CP035426
Coordinates   1089558..1090220 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain emm57     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1084558..1095220
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT73_RS09115 - 1084759..1084896 (-) 138 WP_281726975.1 hypothetical protein -
  ETT73_RS09040 (ETT73_05540) - 1084893..1085120 (-) 228 WP_063631477.1 serine hydrolase -
  ETT73_RS05550 (ETT73_05545) - 1085121..1085354 (-) 234 WP_002983979.1 hypothetical protein -
  ETT73_RS05555 (ETT73_05550) sodA 1085521..1086126 (-) 606 WP_002983977.1 superoxide dismutase SodA -
  ETT73_RS05560 (ETT73_05555) holA 1086223..1087263 (-) 1041 WP_136114156.1 DNA polymerase III subunit delta -
  ETT73_RS05565 (ETT73_05560) comEC/celB 1087334..1089577 (-) 2244 WP_023079940.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ETT73_RS05570 (ETT73_05565) comEA/celA/cilE 1089558..1090220 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  ETT73_RS05575 (ETT73_05570) - 1090420..1091160 (-) 741 WP_002989170.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ETT73_RS05580 (ETT73_05575) - 1091278..1092054 (+) 777 WP_010922438.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ETT73_RS05585 (ETT73_05580) - 1092044..1092322 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  ETT73_RS05590 (ETT73_05585) - 1092346..1094346 (-) 2001 WP_111693287.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=300815 ETT73_RS05570 WP_002995626.1 1089558..1090220(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm57]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=300815 ETT73_RS05570 WP_002995626.1 1089558..1090220(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm57]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405