Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   SP70585_RS00150 Genome accession   NC_012468
Coordinates   22901..23137 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae 70585     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 17901..28137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS11880 (SP70585_0023) - 21901..22110 (+) 210 Protein_15 transposase -
  SP70585_RS11885 - 22119..22635 (-) 517 Protein_16 ISL3 family transposase -
  SP70585_RS00150 (SP70585_0026) comW 22901..23137 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  SP70585_RS00155 (SP70585_0027) - 23368..24654 (+) 1287 WP_041170973.1 adenylosuccinate synthase -
  SP70585_RS00160 (SP70585_0028) - 24896..26044 (-) 1149 WP_000876735.1 site-specific integrase -
  SP70585_RS00165 (SP70585_0029) - 26216..27130 (-) 915 WP_000690123.1 HIRAN domain-containing protein -
  SP70585_RS00170 (SP70585_0030) - 27142..27525 (-) 384 WP_000136460.1 ImmA/IrrE family metallo-endopeptidase -
  SP70585_RS00175 (SP70585_0031) - 27538..27903 (-) 366 WP_000484469.1 helix-turn-helix domain-containing protein -

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=29969 SP70585_RS00150 WP_000939546.1 22901..23137(+) (comW) [Streptococcus pneumoniae 70585]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=29969 SP70585_RS00150 WP_000939546.1 22901..23137(+) (comW) [Streptococcus pneumoniae 70585]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGGTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987

  comW Streptococcus pneumoniae D39

98.718

100

0.987

  comW Streptococcus pneumoniae R6

98.718

100

0.987

  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756


Multiple sequence alignment