Detailed information NTG0299561

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: C2G35_RS00490
• Genome accession: NZ_CP030137
• Coordinates: 102488..103375 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain M51
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 97488..108375

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2G35_RS00460 (C2G35_00455)	-	98220..98981 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
C2G35_RS00465 (C2G35_00460)	-	99226..99681 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
C2G35_RS14780 (C2G35_00465)	-	99803..99904 (+)	102	WP_000731972.1	SE2200 family small protein	-
C2G35_RS00475 (C2G35_00470)	-	99964..101388 (-)	1425	WP_000953744.1	alkaline phosphatase	-
C2G35_RS00480 (C2G35_00475)	-	101586..101786 (+)	201	WP_000604728.1	hypothetical protein	-
C2G35_RS00485 (C2G35_00480)	braR	101812..102477 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
C2G35_RS00490 (C2G35_00485)	braS	102488..103375 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
C2G35_RS00495 (C2G35_00490)	-	103483..104238 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
C2G35_RS00500 (C2G35_00495)	-	104235..106235 (+)	2001	WP_000776751.1	ABC transporter permease	-
C2G35_RS00505 (C2G35_00500)	-	106894..107007 (+)	114	WP_011447078.1	hypothetical protein	-
C2G35_RS00515 (C2G35_00510)	-	107389..107649 (+)	261	WP_001789910.1	hypothetical protein	-
C2G35_RS00520 (C2G35_00515)	-	107659..108156 (+)	498	WP_001065268.1	glutathione peroxidase	-
C2G35_RS00525 (C2G35_00520)	-	108264..108356 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=299561 C2G35_RS00490 WP_000143419.1 102488..103375(+) (braS) [Staphylococcus aureus strain M51]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=299561 C2G35_RS00490 WP_000143419.1 102488..103375(+) (braS) [Staphylococcus aureus strain M51]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997