Detailed information NTG0297795

Bioinformatically predicted

Overview

• Name: rexA
• Type: Machinery gene
• Locus tag: EQH17_RS05480
• Genome accession: NZ_CP035263
• Coordinates: 1108018..1111668 (-)
• Length: 1216 a.a.
• NCBI ID: WP_000767235.1
• Uniprot ID: B2IPX3
• Organism: Streptococcus pneumoniae strain TVO_1901922
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1103018..1116668

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH17_RS05475 (EQH17_05785)	-	1106670..1107848 (-)	1179	WP_000174775.1	hypothetical protein	-
EQH17_RS05480 (EQH17_05795)	rexA	1108018..1111668 (-)	3651	WP_000767235.1	helicase-exonuclease AddAB subunit AddA	Machinery gene
EQH17_RS05485 (EQH17_05800)	rexB	1111665..1114940 (-)	3276	WP_000772324.1	ATP-dependent nuclease subunit B	Machinery gene
EQH17_RS05490 (EQH17_05805)	-	1115140..1115295 (-)	156	Protein_1102	diacylglycerol kinase family lipid kinase	-
EQH17_RS05495 (EQH17_05815)	-	1115466..1116227 (+)	762	Protein_1103	IS630 family transposase	-

Sequence

Protein

• Length: 1216 a.a.
• Molecular weight: 140272.07 Da
• Isoelectric Point: 5.6806

>NTDB_id=297795 EQH17_RS05480 WP_000767235.1 1108018..1111668(-) (rexA) [Streptococcus pneumoniae strain TVO_1901922]
MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNILVSASAGSGKTFVMAERILDQLARGVEISQLFISTFT
VKAATELKERLEKKISKKIQETDDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWLSKSFLKGFEKADFTSEKEKLTE
QIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEIDSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADL
KPLADTYNEERKTQFAKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYTIEILE
NFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQEGKLIL
LKENFRSSSEVLSATNDVFERLMDQEVGEINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMR
LVIKEILKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNPLQDYALVA
LMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKASSQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIW
KIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIHKS
KGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEELQLASYSEQM
RLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTRE
AIGELETKSPLRDSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGVEIAGQGQSVG
KKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAFFDTVLGQEILAN
TDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIKNIE
KYLILLGKDEVQVVKV

Nucleotide

• Length: 3651 bp

>NTDB_id=297795 EQH17_RS05480 WP_000767235.1 1108018..1111668(-) (rexA) [Streptococcus pneumoniae strain TVO_1901922]
ATGAAGCTTATTCCCTTTTTAAGTGAGGAGGAGATTCAAAAACTGCAAGAAGCAGAAGCAAATTCGAGCAAGGAACAGAA
GAAAACTGCCGAGCAAATCGAAGCTATCTACACTTCTGGCCAGAATATCCTGGTCTCAGCATCGGCTGGTTCTGGAAAGA
CCTTTGTCATGGCAGAGCGCATTCTGGACCAATTGGCGCGTGGTGTCGAAATTTCTCAACTCTTTATCTCAACCTTTACG
GTCAAGGCTGCAACTGAACTTAAAGAACGTTTAGAGAAAAAAATCAGCAAGAAAATCCAAGAAACAGATGATGTCGACCT
CAAACAACACTTGGGACGCCAGTTGGCAGACCTACCCAACGCTGCCATCGGAACCATGGACTCTTTCACACAAAAATTCC
TTGGCAAACATGGTTATCTGCTTGATATTGCACCTAATTTCCGTATTTTACAAAACCAAAGCGAGCAACTTCTTCTCGAA
AACGAAGTCTTTCATGAGGTCTTTGAAGCGCATTACCAAGGTAAACAGAAAGAGACCTTTAGTCATTTGCTGAAAAACTT
TGCTGGACGTGGCAAGGACGAACGGGGTCTGCGCCAGCAGGTCTATAAAATCTATGACTTCCTCCAATCCACCAGTAATC
CTCAAAAGTGGCTGAGTAAATCTTTCCTCAAAGGTTTTGAGAAAGCTGATTTTACCAGTGAAAAAGAAAAACTGACTGAG
CAAATCAAACAAGCCCTTTGGGATTTGGAAAGCTTTTTCCGTTACCATCTGGATAACGATGCCAAGGAGTTTGCAAAGGC
TGCCTATTTAGAAAATGTTCAGTTAATTCTGGATGAAATTGACTCCCTAAATCAGGAGTCCGATAGTCAGGCTTATCAGG
CAGTGCTTGCGCGTGTTGTCGCCATCTCTAAGGAGAAAAACGGTCGAGCTCTGACTAATGCCAGCCGTAAGGCTGATTTG
AAGCCCCTGGCTGATACCTACAACGAAGAGAGAAAGACCCAGTTTGCTAAACTAGGACAATTATCAGACCAGATAGCGAT
TCTCGACTATCAAGAACGTTATCATGGAGACACTTGGAAACTAGCTAAAACCTTCCAATCTTTCATGAGCGATTTTGTAG
AGGCTTATCGTCAGAGAAAACGACAGGAAAATGCCTTTGAATTCGCTGATATCAGCCATTACACCATTGAGATTTTAGAG
AATTTCCCACAAGTTCGTGAGTCTTATCAGGAGCGCTTCCATGAAGTCATGGTCGATGAGTATCAGGATACCAACCATAT
TCAAGAACGGATGCTGGAATTGTTGTCTAATGGCCACAATCGCTTTATGGTGGGAGATATCAAGCAATCCATCTATCGTT
TCCGTCAGGCAGACCCGCAGATTTTCAATGAGAAATTCCAACGCTATGCGCAAAATCCCCAAGAAGGCAAGCTCATTCTC
CTCAAGGAAAATTTCCGTAGTAGTTCAGAAGTGCTGTCAGCAACCAATGATGTCTTTGAACGTCTCATGGACCAAGAGGT
CGGCGAAATCAACTATGATAACAAGCACCAGCTTGTTTTTGCCAATACCAAACTGACTCCCAATCCAGACAACAAGGCAG
AATTTCTCCTCTACGACAAGGACGATACAGGTGAGGAAGAAGAGAGTCAAACAGAAACGAAACTAACAGGCGAAATGCGC
TTAGTTATCAAGGAGATCCTTAAACTTCATCAGGAAAAAGGTGTTGCCTTTAAGGAAATTGCCCTTCTGACCTCTAGTCG
TAATCGTAATGACCAAATTCTACTTGCCCTGTCTGAGTACGGGATTCCTGTCAAAACTGACGGAGAGCAAAACAATTATC
TCCAATCCCTAGAAGTGCAAGTCATGCTAGACACCCTTCGTGTCATTCACAATCCCCTGCAAGACTACGCCTTGGTTGCC
CTTATGAAGTCTCCAATGTTTGGTTTTGATGAGGATGAGCTAGCACGTTTGTCCCTTCAGAAAGCAGAGGATAAAGCCCA
CGAAAATCTCTATGAGAAACTGGTCAATGCACAAAAAAAGGCAAGTAGTCAAAAAGGCTTGATTCACACAGCTCTAGCTG
AAAAACTAAAGCAATTCATGGATATCCTAGCTTCTTGGCGCTTGTATGCCAAACCCCACTCTCTCTATGACTTGATTTGG
AAGATTTACAACGACCGTTTTTATTATGACTATGTTGGGGCTTTGCCGAATGGTCCTGCTAGGCAGGCCAATCTCTATGC
CCTAGCACTGCGTGCTGATCAATTTGAAAAGAGCAATTTCAAAGGTTTGTCGCGTTTTATTCGTATGATTGACCAAGTCT
TAGAAGCCCAGCACGATTTGGCAAGCGTGGCCGTCGCACCGCCAAAAGATGCAGTAGAGCTCATGACCATCCACAAGAGT
AAAGGGCTGGAGTTTCCTTACGTCTTTATCCTCAATATGGATCAAGATTTCAACAAGCAGGACTCTATGTCAGAAGTCAT
TCTCAGTCGTCAGAATGGTCTTGGTGTCAAATATATTGCCAAGATGGAGACAGGGGCAGTAGAAGACCACTATCCTAAAA
CCATCAAACTCTCCATTCCTAGTCTGACCTATAGGCAGAACGAAGAGGAATTACAGCTAGCAAGCTATTCTGAGCAGATG
CGTTTGCTGTATGTTGCTATGACGCGGGCTGAGAAAAAGCTCTATCTTGTCGGCAAGGGTTCTCGTGAAAAGCTGGAAGC
CAAGCAATACCCAGCAGCCAAAAATGGGAAACTAAATAGCAATACTAGACTGCAAGCACGGAATTTCCAAGATTGGCTTT
GGGCTATCAGTAAAGTGTTTACTAAGGACAAGCTCAACTTTAGTTATCGTTTTATTGGCGAAGATCAGTTGACCAGAGAA
GCTATCGGAGAGTTGGAAACCAAGAGTCCTCTCCGAGATAGCTCCCAAGCAGACAATCGTCAGTCAGATACCATCAAAGA
AGCTCTGGAAATGCTGAAGGAGGTGGAAGTTTATAATACTCTTCACCGCGCAGCTATTGAACTTCCTAGTGTTCAAACCC
CAAGTCAAATCAAGAAATTCTACGAACCAGTTATGGATATGGAAGGTGTCGAGATTGCTGGTCAAGGTCAGTCAGTAGGC
AAGAAAATCAGCTTCGATTTGCCAGATTTTTCAACCAAAGAAAAGGTAACTGGAGCTGAGATTGGTAGTGCTACTCACGA
ACTCATGCAGAGAATTGACCTCAGCCAGCAACTAACCCTTGCTAGCCTAACAGAAACACTCAAACAAGTTCAAACTAGCC
AAGCTGTCAGAGACAAGATCAATCTTGATAAAATTCTTGCTTTCTTTGACACAGTACTCGGTCAGGAAATTCTTGCTAAT
ACCGACCATCTCTATCGCGAGCAACCTTTCTCCATGCTCAAACGAGACCAAAAGAGTCAGGAAGACTTTGTTGTCCGTGG
TATCCTTGATGGCTATCTGCTTTACGAAAACAAAATTGTTCTGTTCGACTACAAGACAGACCGCTATGATGAACCAAGTC
AACTCGTAGACCGCTATCGTGGTCAGTTAGCTCTATACGAAGAGGCTTTATCACGAGCCTATTCGATTAAAAATATTGAA
AAATACTTGATTTTACTCGGTAAAGACGAGGTTCAAGTTGTAAAAGTATAA

Domains

Predicted by InterProScan.

• UvrD-like helicase C-terminal domain (UvrD_C) (479-896)

• UvrD/REP helicase N-terminal domain (UvrD-helicase) (29-469)

• PD-(D/E)XK nuclease superfamily (PDDEXK_1) (1054-1193)

3D structure

• AlphaFold DB: B2IPX3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rexA	Streptococcus pneumoniae R6	98.684	100	0.987