Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SUB_RS00365 Genome accession   NC_012004
Coordinates   62035..62949 (+) Length   304 a.a.
NCBI ID   WP_269441089.1    Uniprot ID   -
Organism   Streptococcus uberis 0140J     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 57035..67949
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS00345 (SUB0053) purD 57454..58716 (+) 1263 WP_012657619.1 phosphoribosylamine--glycine ligase -
  SUB_RS00350 (SUB0054) purE 58762..59250 (+) 489 WP_012657620.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  SUB_RS00355 (SUB0055) purK 59237..60310 (+) 1074 WP_012657621.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  SUB_RS00360 (SUB0056) purB 60624..61916 (+) 1293 WP_012657622.1 adenylosuccinate lyase -
  SUB_RS00365 (SUB0057) comR 62035..62949 (+) 915 WP_269441089.1 helix-turn-helix domain-containing protein Regulator
  SUB_RS09690 - 63049..63147 (+) 99 WP_198433762.1 quorum-sensing system DWW-type pheromone -
  SUB_RS00370 (SUB0059) ruvB 63179..64183 (+) 1005 WP_012657625.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  SUB_RS00375 (SUB0060) - 64434..64862 (+) 429 WP_012657626.1 low molecular weight protein-tyrosine-phosphatase -
  SUB_RS00380 (SUB0061) - 64867..65280 (+) 414 WP_012657627.1 membrane protein -
  SUB_RS00385 (SUB0062) - 65277..67055 (+) 1779 WP_012657628.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 36287.81 Da        Isoelectric Point: 5.1909

>NTDB_id=29629 SUB_RS00365 WP_269441089.1 62035..62949(+) (comR) [Streptococcus uberis 0140J]
MKELRKKKQMTREALCGDESELSVRQLARIESGQSNPSLAKALFIAKKLGVPLSDFVNPKELDLPKRYQELKYLILRHPT
YMNTDSIEERESQFDIIFEDYYADLPEEEQVLIDRLRSRFEVYQSGNSVYGQDLLLEYIDQIKKKKTYDLNDIFFIDLYL
TCGYVSSFKETLFDKGIFECFTSKLILLEEKLDFKDLFLLNNVLMTAIAVGLTLEEYVKIRTLLNVCRRIMTITQDFQRM
PIYYMYEWRYTLFHEKDFRKAPYYYQQSLLFARTHGDEYLKTMIVNAWQEDQDKVKTLESQKEI

Nucleotide


Download         Length: 915 bp        

>NTDB_id=29629 SUB_RS00365 WP_269441089.1 62035..62949(+) (comR) [Streptococcus uberis 0140J]
ATGAAAGAATTGAGAAAGAAAAAACAGATGACACGAGAGGCTCTTTGTGGTGATGAGTCGGAATTATCAGTTCGTCAACT
AGCAAGAATTGAATCTGGACAATCTAATCCTTCTCTAGCCAAAGCTCTTTTTATTGCAAAAAAATTAGGAGTCCCTTTGT
CTGATTTCGTCAATCCTAAAGAACTTGACCTGCCAAAACGCTATCAAGAATTGAAGTATTTGATTTTAAGACATCCGACT
TATATGAATACAGACTCTATAGAAGAAAGAGAATCCCAGTTTGATATCATTTTTGAAGATTATTATGCGGATTTGCCTGA
AGAAGAACAGGTACTCATTGATCGCTTACGGTCTAGATTTGAAGTTTATCAAAGTGGGAATAGCGTTTATGGTCAAGATC
TTTTGCTTGAATATATTGATCAAATAAAAAAGAAAAAAACCTATGATCTGAATGATATCTTTTTTATAGATTTATATTTA
ACCTGTGGTTATGTCTCTTCATTTAAAGAAACACTTTTTGATAAAGGAATCTTTGAATGCTTTACCAGTAAGTTGATCCT
CTTAGAAGAAAAGTTAGATTTCAAAGATTTATTTTTACTCAACAATGTTTTGATGACTGCTATTGCAGTTGGATTAACCC
TTGAAGAATATGTAAAAATACGGACACTATTAAATGTCTGTCGTCGTATTATGACAATTACGCAAGATTTTCAAAGAATG
CCTATTTATTATATGTATGAGTGGCGTTATACCCTATTTCATGAAAAAGATTTCCGAAAAGCTCCCTATTACTATCAACA
GTCCTTGCTATTTGCCCGGACACATGGGGATGAGTATTTAAAAACTATGATAGTAAATGCTTGGCAAGAGGATCAAGATA
AGGTAAAGACATTGGAAAGTCAGAAGGAAATTTAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(65-288)

Helix-turn-helix (HTH_3)

(1-56)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

47.423

95.724

0.454
  comR Streptococcus mutans UA159

42.612

95.724

0.408
  comR Streptococcus pyogenes MGAS8232

41.924

95.724

0.401
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.249

96.382

0.378

Multiple sequence alignment