Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   EHF39_RS06415 Genome accession   NZ_CP033908
Coordinates   1225951..1226613 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain RLGH     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1220951..1231613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHF39_RS06395 (EHF39_06395) - 1221601..1221747 (-) 147 WP_011528767.1 hypothetical protein -
  EHF39_RS06400 (EHF39_06400) sodA 1221914..1222519 (-) 606 WP_002983977.1 superoxide dismutase SodA -
  EHF39_RS06405 (EHF39_06405) holA 1222616..1223656 (-) 1041 WP_011017949.1 DNA polymerase III subunit delta -
  EHF39_RS06410 (EHF39_06410) comEC/celB 1223727..1225970 (-) 2244 WP_011528768.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EHF39_RS06415 (EHF39_06415) comEA/celA/cilE 1225951..1226613 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  EHF39_RS06420 (EHF39_06420) - 1226813..1227553 (-) 741 WP_021299345.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  EHF39_RS06425 (EHF39_06425) - 1227671..1228447 (+) 777 WP_010922438.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  EHF39_RS06430 (EHF39_06430) - 1228437..1228715 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  EHF39_RS06435 (EHF39_06435) - 1228739..1230740 (-) 2002 Protein_1191 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=285929 EHF39_RS06415 WP_002995626.1 1225951..1226613(-) (comEA/celA/cilE) [Streptococcus pyogenes strain RLGH]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=285929 EHF39_RS06415 WP_002995626.1 1225951..1226613(-) (comEA/celA/cilE) [Streptococcus pyogenes strain RLGH]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGATCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405

Multiple sequence alignment