Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   EHF40_RS09980 Genome accession   NZ_CP033907
Coordinates   391943..392161 (+) Length   72 a.a.
NCBI ID   WP_011528334.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Duke-Large     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 386943..397161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHF40_RS02090 (EHF40_02090) - 387952..388527 (+) 576 WP_009880369.1 uracil-DNA glycosylase family protein -
  EHF40_RS02095 (EHF40_02095) ybeY 388686..389183 (+) 498 WP_002985748.1 rRNA maturation RNase YbeY -
  EHF40_RS02100 (EHF40_02100) - 389164..389571 (+) 408 WP_002985746.1 diacylglycerol kinase -
  EHF40_RS02105 (EHF40_02105) era 389691..390587 (+) 897 WP_003047080.1 GTPase Era -
  EHF40_RS02110 (EHF40_02110) - 390607..391083 (+) 477 WP_014635332.1 NUDIX domain-containing protein -
  EHF40_RS09975 (EHF40_02115) - 391388..391642 (-) 255 WP_010921971.1 hypothetical protein -
  EHF40_RS09980 comE/blpR 391943..392161 (+) 219 WP_011528334.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  EHF40_RS09985 - 392382..393964 (-) 1583 Protein_351 ABC transporter transmembrane domain-containing protein -
  EHF40_RS02140 (EHF40_02140) - 394262..394486 (+) 225 WP_002994580.1 Blp family class II bacteriocin -
  EHF40_RS09830 - 394464..394640 (+) 177 WP_002994581.1 hypothetical protein -
  EHF40_RS10100 - 395330..395458 (+) 129 WP_002994583.1 hypothetical protein -
  EHF40_RS02150 (EHF40_02150) - 395856..396083 (+) 228 WP_042769846.1 Blp family class II bacteriocin -
  EHF40_RS02155 (EHF40_02155) - 396132..396449 (+) 318 WP_021299375.1 hypothetical protein -

Sequence

Protein


Download         Length: 72 a.a.        Molecular weight: 8680.16 Da        Isoelectric Point: 10.5045

>NTDB_id=285872 EHF40_RS09980 WP_011528334.1 391943..392161(+) (comE/blpR) [Streptococcus pyogenes strain Duke-Large]
MVLYSTRERIEFYGELSEIVKQEPRLFQCHRSFVVNPYNISSIQRLERKIYLKKRFILSSIKAKSYCSKRSS

Nucleotide


Download         Length: 219 bp        

>NTDB_id=285872 EHF40_RS09980 WP_011528334.1 391943..392161(+) (comE/blpR) [Streptococcus pyogenes strain Duke-Large]
TTGGTTCTTTATTCTACTAGAGAAAGGATTGAATTTTATGGGGAGTTATCTGAAATCGTTAAGCAAGAACCAAGATTATT
TCAATGCCATCGATCATTTGTTGTTAATCCCTACAATATATCTTCAATACAACGATTAGAACGTAAGATTTATTTAAAAA
AACGGTTCATCTTGTCTAGTATCAAGGCTAAAAGTTACTGCTCTAAAAGAAGCAGTTGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(3-56)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

56.604

73.611

0.417