Detailed information NTG0268052

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DZN94_RS08855
• Genome accession: NZ_CP031633
• Coordinates: 1763553..1764320 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS11115
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1758553..1769320

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZN94_RS08840 (DZN94_08835)	hexB	1759071..1761053 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
DZN94_RS08845 (DZN94_08840)	-	1761148..1762299 (-)	1152	WP_003058754.1	site-specific integrase	-
DZN94_RS09660 (DZN94_08845)	-	1762548..1762691 (+)	144	WP_011185066.1	putative holin-like toxin	-
DZN94_RS08855 (DZN94_08850)	irvR	1763553..1764320 (-)	768	WP_003058809.1	S24 family peptidase	Regulator
DZN94_RS08860 (DZN94_08855)	-	1764474..1764680 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DZN94_RS08865 (DZN94_08860)	-	1764714..1764887 (+)	174	Protein_1644	helix-turn-helix transcriptional regulator	-
DZN94_RS08870 (DZN94_08865)	-	1764935..1765342 (+)	408	WP_002992501.1	hypothetical protein	-
DZN94_RS09665	-	1765355..1765477 (+)	123	WP_011285272.1	hypothetical protein	-
DZN94_RS08875 (DZN94_08870)	-	1765760..1766281 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
DZN94_RS08880 (DZN94_08875)	-	1766529..1766702 (+)	174	WP_000132665.1	hypothetical protein	-
DZN94_RS08885 (DZN94_08880)	-	1766920..1767093 (+)	174	WP_000074663.1	hypothetical protein	-
DZN94_RS08890 (DZN94_08885)	-	1767255..1767686 (+)	432	WP_136302445.1	hypothetical protein	-
DZN94_RS08895 (DZN94_08890)	-	1767788..1768120 (+)	333	WP_021775546.1	hypothetical protein	-
DZN94_RS08900 (DZN94_08895)	-	1768120..1768311 (+)	192	WP_021340709.1	hypothetical protein	-
DZN94_RS08905 (DZN94_08900)	-	1768323..1768652 (+)	330	WP_003058810.1	hypothetical protein	-
DZN94_RS08910 (DZN94_08905)	-	1768655..1768927 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=268052 DZN94_RS08855 WP_003058809.1 1763553..1764320(-) (irvR) [Streptococcus pyogenes strain MGAS11115]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=268052 DZN94_RS08855 WP_003058809.1 1763553..1764320(-) (irvR) [Streptococcus pyogenes strain MGAS11115]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4