Detailed information NTG0266891

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: C2E46_RS02880
• Genome accession: NZ_CP026082
• Coordinates: 516425..517498 (+)
• Length: 357 a.a.
• NCBI ID: WP_000790650.1
• Uniprot ID: A0A0H1YUL6
• Organism: Streptococcus agalactiae strain YZ1605
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 511425..522498

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2E46_RS02850 (C2E46_02915)	-	512316..513380 (+)	1065	WP_161501813.1	MmcQ/YjbR family DNA-binding protein	-
C2E46_RS02855 (C2E46_02920)	asnA	513495..514487 (+)	993	WP_000748010.1	aspartate--ammonia ligase	-
C2E46_RS02860 (C2E46_02925)	-	514532..514981 (-)	450	WP_000592264.1	bacteriocin transport accessory protein	-
C2E46_RS02865 (C2E46_02930)	rsmD	515112..515651 (+)	540	WP_001872952.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
C2E46_RS02870 (C2E46_02935)	-	515663..515953 (+)	291	WP_000384889.1	hypothetical protein	-
C2E46_RS02875 (C2E46_02940)	coaD	515950..516435 (+)	486	WP_000161889.1	pantetheine-phosphate adenylyltransferase	-
C2E46_RS02880 (C2E46_02945)	sepM	516425..517498 (+)	1074	WP_000790650.1	SepM family pheromone-processing serine protease	Regulator
C2E46_RS02885 (C2E46_02950)	-	517573..518907 (+)	1335	WP_000137519.1	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
C2E46_RS02890 (C2E46_02955)	-	518976..519554 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
C2E46_RS02895 (C2E46_02960)	rlmN	519605..520711 (+)	1107	WP_115343274.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
C2E46_RS02900 (C2E46_02965)	-	520711..521226 (+)	516	WP_161501814.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39145.29 Da
• Isoelectric Point: 10.4045

>NTDB_id=266891 C2E46_RS02880 WP_000790650.1 516425..517498(+) (sepM) [Streptococcus agalactiae strain YZ1605]
MKNKDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVSSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKQGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=266891 C2E46_RS02880 WP_000790650.1 516425..517498(+) (sepM) [Streptococcus agalactiae strain YZ1605]
GTGAAGAATAAAGATCCAAAAAGAAAACATAAAAGTTTGCTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTGGTGAGGCTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATCATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTAGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGCACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAACAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (241-307)

3D structure

• AlphaFold DB: A0A0H1YUL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658