Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RK83_RS14100 Genome accession   NZ_CP026069
Coordinates   2692768..2693484 (+) Length   238 a.a.
NCBI ID   WP_000688493.1    Uniprot ID   G9IE49
Organism   Staphylococcus aureus strain FDAARGOS_25     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2687768..2698484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RK83_RS14070 (RK83_014070) - 2687985..2688611 (+) 627 WP_000522381.1 nitroreductase family protein -
  RK83_RS14075 (RK83_014075) - 2688972..2689757 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  RK83_RS15280 hld 2690357..2690437 (-) 81 WP_000046022.1 delta-hemolysin -
  RK83_RS14085 (RK83_014085) - 2690727..2691290 (+) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  RK83_RS14090 (RK83_014090) - 2691293..2691436 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide -
  RK83_RS14095 (RK83_014095) - 2691466..2692749 (+) 1284 WP_000447888.1 sensor histidine kinase -
  RK83_RS14100 (RK83_014100) agrA 2692768..2693484 (+) 717 WP_000688493.1 LytTR family DNA-binding domain-containing protein Regulator
  RK83_RS14105 (RK83_014105) - 2693559..2693668 (+) 110 Protein_2636 hypothetical protein -
  RK83_RS14110 (RK83_014110) - 2693856..2694815 (-) 960 WP_001253315.1 carbohydrate kinase -
  RK83_RS14115 (RK83_014115) - 2694812..2696296 (-) 1485 WP_000141432.1 glycoside hydrolase family 32 protein -
  RK83_RS14120 (RK83_014120) - 2696445..2697395 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27920.92 Da        Isoelectric Point: 6.3009

>NTDB_id=266496 RK83_RS14100 WP_000688493.1 2692768..2693484(+) (agrA) [Staphylococcus aureus strain FDAARGOS_25]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKK

Nucleotide


Download         Length: 717 bp        

>NTDB_id=266496 RK83_RS14100 WP_000688493.1 2692768..2693484(+) (agrA) [Staphylococcus aureus strain FDAARGOS_25]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAAATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-236)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G9IE49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

99.58

0.996

Multiple sequence alignment