Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DV129_RS01940 Genome accession   NZ_CP031247
Coordinates   354890..355354 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain M23734     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 349890..360354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS12585 - 350095..350169 (+) 75 Protein_363 dihydroxyacetone kinase subunit L -
  DV129_RS01915 dhaM 350169..350549 (+) 381 Protein_364 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  DV129_RS01920 - 351116..352462 (+) 1347 WP_012677075.1 IS1380-like element ISSpn5 family transposase -
  DV129_RS01925 - 352715..353428 (+) 714 WP_000499437.1 YjjG family noncanonical pyrimidine nucleotidase -
  DV129_RS01930 - 353442..354089 (+) 648 WP_001809355.1 hypothetical protein -
  DV129_RS01935 - 354227..354880 (+) 654 WP_000401329.1 uracil-DNA glycosylase -
  DV129_RS01940 mutX 354890..355354 (+) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  DV129_RS01945 - 355367..356635 (+) 1269 WP_000924489.1 dihydroorotase -
  DV129_RS01950 - 356649..356909 (+) 261 WP_001105925.1 hypothetical protein -
  DV129_RS01955 pdrM 356920..358281 (+) 1362 WP_000278534.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  DV129_RS01960 - 358435..359403 (+) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=263226 DV129_RS01940 WP_001135768.1 354890..355354(+) (mutX) [Streptococcus pneumoniae strain M23734]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=263226 DV129_RS01940 WP_001135768.1 354890..355354(+) (mutX) [Streptococcus pneumoniae strain M23734]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987