Detailed information NTG0026240

Bioinformatically predicted

Overview

• Name: lytF
• Type: Regulator
• Locus tag: SSA_RS00275
• Genome accession: NC_009009
• Coordinates: 42140..44089 (-)
• Length: 649 a.a.
• NCBI ID: WP_011836292.1
• Uniprot ID: A3CJZ8
• Organism: Streptococcus sanguinis SK36
• Function: cell lysis (predicted from homology) Cell lysis

Genomic Context

Location: 37140..49089

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSA_RS00255 (SSA_0032)	purM	38078..39100 (+)	1023	WP_011836288.1	phosphoribosylformylglycinamidine cyclo-ligase	-
SSA_RS00260 (SSA_0033)	purN	39097..39660 (+)	564	WP_011836289.1	phosphoribosylglycinamide formyltransferase	-
SSA_RS00265 (SSA_0034)	-	39738..40451 (+)	714	WP_164925982.1	hypothetical protein	-
SSA_RS00270 (SSA_0035)	purH	40470..42017 (+)	1548	WP_033179090.1	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	-
SSA_RS00275 (SSA_0036)	lytF	42140..44089 (-)	1950	WP_011836292.1	murein hydrolase LytF	Regulator
SSA_RS00280 (SSA_0037)	purD	44412..45674 (+)	1263	WP_011836293.1	phosphoribosylamine--glycine ligase	-
SSA_RS00285 (SSA_0039)	purE	45973..46461 (+)	489	WP_002926479.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SSA_RS00290 (SSA_0040)	purK	46448..47539 (+)	1092	WP_002926478.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SSA_RS00300 (SSA_0041)	-	47802..48029 (+)	228	WP_011836294.1	hypothetical protein	-
SSA_RS00305 (SSA_0042)	-	48033..48731 (+)	699	WP_011836295.1	aspartate/glutamate racemase family protein	-
SSA_RS00310	-	48728..48811 (+)	84	Protein_38	hypothetical protein	-

Sequence

Protein

• Length: 649 a.a.
• Molecular weight: 72154.65 Da
• Isoelectric Point: 6.8215

>NTDB_id=26240 SSA_RS00275 WP_011836292.1 42140..44089(-) (lytF) [Streptococcus sanguinis SK36]
MKKYQKLFLLSGAVLGLFASHSTVHATETPESEVKILGPTDRASNVDVTVNDRTVSISYTRSQAQEPYLIAHAVWSEENG
QDDLKWYDTPQTPITDIDLSNHPGYGTFHVHTYIRIGERLVALNATTFHVDKPASKTNASVSGGTGRISFSRNKDQTHSK
IVHAVWSEEKGSDDLQWYDAGEESTEFNLSKHRGYGRYFVDTYENVNGKMIFLSGTTFHLENPKPIIETSFPQTGIMEIT
VKNVPDTMYKVVLPTWSDKKGQDDLQWYEASKNPDGSYSARVELRKHNYDTGTYNIHLYGQSYVQPESTGITGTTVQVDS
GKLPSDEEQKPLFTVENINPKQGTYTVKTTETSLSKPIQSVRVPIWSTSNQSNLKWYAATPNGDGSFSATFDIRNHQALS
GTYNNHVYVTYKDGSERSYAADAVSMSTDQIQAKVAVRKTEANRYEVTVTDAYGDGDIILPTWSEVNGQDDIKWYTANKV
GNGTYKFTVDTQNHKGSGLFNTHVYRRKAGQLIGLTGTSYQVEKSSVQSANIQPNYAAANATTYPVGQCTWGAKALAPWA
GNYWGNGGQWAASARRAGFRTGSTPEVGAIACWDDGGYGHVGVVTHVESNTRIQIQESNYLGKQYISNFRGWFDPTASYW
GRLTYIYPK

Nucleotide

• Length: 1950 bp

>NTDB_id=26240 SSA_RS00275 WP_011836292.1 42140..44089(-) (lytF) [Streptococcus sanguinis SK36]
ATGAAGAAATATCAAAAACTGTTTTTATTATCCGGAGCTGTCCTAGGTCTCTTTGCGAGCCACTCAACAGTCCATGCGAC
CGAAACGCCTGAATCTGAAGTCAAAATTCTAGGCCCTACTGATCGTGCCAGCAATGTCGATGTGACTGTGAACGATCGTA
CAGTCTCTATTAGTTATACCCGTTCTCAAGCTCAAGAACCTTATCTTATTGCTCATGCTGTTTGGTCTGAAGAAAACGGA
CAAGATGATTTGAAATGGTATGATACACCACAAACACCCATCACTGACATTGACTTAAGCAACCATCCAGGATATGGTAC
GTTTCATGTTCATACTTACATACGGATAGGAGAGCGCTTGGTAGCTCTAAATGCCACTACCTTTCATGTAGATAAACCAG
CTAGTAAAACGAATGCATCCGTCTCAGGAGGTACAGGACGCATTAGTTTTTCCCGTAACAAAGACCAAACTCACTCAAAG
ATTGTCCATGCTGTCTGGTCAGAGGAAAAAGGCAGCGACGACCTTCAGTGGTATGACGCAGGAGAAGAATCAACTGAATT
TAATCTTTCCAAACATCGTGGTTATGGACGATACTTCGTTGACACTTATGAAAATGTAAACGGAAAAATGATTTTCCTAT
CTGGTACTACGTTCCATCTTGAAAATCCGAAACCGATAATCGAAACCAGCTTCCCTCAGACCGGTATCATGGAAATTACT
GTCAAAAACGTACCTGACACTATGTATAAAGTAGTTCTTCCTACTTGGTCTGATAAGAAAGGGCAAGATGATCTACAATG
GTACGAAGCAAGCAAAAATCCGGATGGTAGCTACAGCGCTCGGGTGGAACTCAGAAAGCATAACTACGACACTGGAACTT
ACAATATCCACCTTTACGGTCAAAGCTATGTTCAACCGGAATCAACTGGTATAACAGGAACGACAGTTCAAGTTGACAGC
GGAAAATTACCTTCGGACGAGGAACAGAAACCTCTTTTTACTGTGGAAAATATCAACCCCAAACAAGGGACCTACACCGT
GAAAACTACCGAAACTAGCTTATCTAAACCTATTCAATCTGTCCGGGTGCCAATTTGGAGCACTAGTAATCAGAGCAATC
TTAAATGGTATGCAGCCACTCCTAACGGAGATGGCTCCTTCAGCGCAACCTTTGATATCCGTAATCACCAGGCTTTGTCT
GGAACCTATAACAACCATGTGTATGTCACCTATAAGGACGGCAGTGAGCGTAGCTACGCAGCAGATGCCGTCTCAATGTC
TACCGACCAAATCCAAGCCAAGGTTGCAGTCAGGAAAACTGAGGCTAATCGCTATGAGGTGACAGTGACAGACGCCTACG
GAGATGGCGATATTATTCTGCCGACTTGGTCAGAAGTCAATGGGCAAGATGATATCAAATGGTATACCGCTAATAAGGTC
GGCAATGGAACATACAAGTTTACCGTAGATACTCAGAATCACAAGGGGAGCGGTCTATTTAACACCCATGTCTATCGTAG
AAAAGCGGGACAGTTAATCGGCCTGACTGGAACTAGCTATCAGGTTGAGAAATCAAGCGTTCAATCAGCTAATATTCAGC
CTAACTATGCCGCTGCTAATGCGACAACTTATCCTGTCGGTCAATGTACTTGGGGAGCCAAAGCTCTAGCTCCTTGGGCT
GGAAATTACTGGGGCAACGGCGGTCAATGGGCAGCTAGTGCCAGAAGAGCTGGATTCCGTACCGGCAGTACACCTGAGGT
TGGTGCCATCGCCTGCTGGGATGACGGTGGCTACGGCCACGTTGGTGTTGTGACTCATGTCGAATCCAATACCCGCATCC
AGATTCAAGAGTCTAACTACCTCGGCAAGCAGTACATCAGCAACTTCCGTGGCTGGTTTGACCCAACTGCTTCCTACTGG
GGCCGCCTGACCTATATCTACCCTAAATAA

Domains

Predicted by InterProScan.

• CHAP domain (CHAP) (542-619)

• GBS Bsp-like repeat (GBS_Bsp-like) (70-116)

• GBS Bsp-like repeat (GBS_Bsp-like) (233-307)

• GBS Bsp-like repeat (GBS_Bsp-like) (335-418)

• GBS Bsp-like repeat (GBS_Bsp-like) (438-514)

• GBS Bsp-like repeat (GBS_Bsp-like) (147-218)

3D structure

• AlphaFold DB: A3CJZ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lytF	Streptococcus gordonii strain NCTC7865	44.952	80.894	0.364
lytF	Streptococcus gordonii str. Challis substr. CH1	44.952	80.894	0.364