Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   CWI64_RS04400 Genome accession   NZ_CP025076
Coordinates   834736..835395 (+) Length   219 a.a.
NCBI ID   WP_000565017.1    Uniprot ID   A0A0E8GKN8
Organism   Streptococcus pneumoniae strain BHN97x     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 829736..840395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI64_RS04375 (CWI64_04375) - 830041..830358 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  CWI64_RS04380 (CWI64_04380) - 830373..831269 (-) 897 WP_000825668.1 PEP phosphonomutase -
  CWI64_RS04385 (CWI64_04385) - 831272..832534 (-) 1263 WP_000413345.1 PTS sugar transporter subunit IIC -
  CWI64_RS04390 (CWI64_04390) - 832814..833992 (+) 1179 WP_000175879.1 ROK family transcriptional regulator -
  CWI64_RS04395 (CWI64_04395) - 834220..834666 (-) 447 WP_000155412.1 GNAT family N-acetyltransferase -
  CWI64_RS04400 (CWI64_04400) cclA/cilC 834736..835395 (+) 660 WP_000565017.1 A24 family peptidase Machinery gene
  CWI64_RS04405 (CWI64_04405) - 835447..836598 (-) 1152 WP_000481749.1 XRE family transcriptional regulator -
  CWI64_RS04410 (CWI64_04410) - 836613..837344 (-) 732 WP_000934017.1 hypothetical protein -
  CWI64_RS04415 (CWI64_04415) - 837573..837674 (+) 102 Protein_838 prepilin peptidase -
  CWI64_RS04420 (CWI64_04420) trpA 837646..838422 (-) 777 WP_001127002.1 tryptophan synthase subunit alpha -
  CWI64_RS04425 (CWI64_04425) trpB 838415..839638 (-) 1224 WP_000331293.1 tryptophan synthase subunit beta -
  CWI64_RS04430 (CWI64_04430) - 839616..840215 (-) 600 WP_000169927.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24879.99 Da        Isoelectric Point: 7.6418

>NTDB_id=258072 CWI64_RS04400 WP_000565017.1 834736..835395(+) (cclA/cilC) [Streptococcus pneumoniae strain BHN97x]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=258072 CWI64_RS04400 WP_000565017.1 834736..835395(+) (cclA/cilC) [Streptococcus pneumoniae strain BHN97x]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E8GKN8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae Rx1

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae D39

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae R6

95.89

100

0.959
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

85.845

100

0.858

Multiple sequence alignment