Detailed information NTG0240267

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: CGU46_RS31635
• Genome accession: NZ_CP022525
• Coordinates: 6579641..6581866 (-)
• Length: 741 a.a.
• NCBI ID: WP_023100928.1
• Uniprot ID: A0A509JMW0
• Organism: Pseudomonas aeruginosa strain Ocean-1175
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 6574641..6586866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGU46_RS31600 (CGU46_31600)	murB	6575031..6576050 (-)	1020	WP_021265002.1	UDP-N-acetylmuramate dehydrogenase	-
CGU46_RS31605 (CGU46_31605)	-	6576047..6576511 (-)	465	WP_003106924.1	low molecular weight protein-tyrosine-phosphatase	-
CGU46_RS31610 (CGU46_31610)	kdsB	6576511..6577275 (-)	765	WP_003091155.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
CGU46_RS31615 (CGU46_31615)	-	6577275..6577460 (-)	186	WP_003091157.1	Trm112 family protein	-
CGU46_RS31620 (CGU46_31620)	lpxK	6577498..6578496 (-)	999	WP_003130692.1	tetraacyldisaccharide 4'-kinase	-
CGU46_RS31625 (CGU46_31625)	-	6578496..6578936 (-)	441	WP_003091161.1	ExbD/TolR family protein	-
CGU46_RS31630 (CGU46_31630)	exbB	6578933..6579568 (-)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
CGU46_RS31635 (CGU46_31635)	comA	6579641..6581866 (-)	2226	WP_023100928.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
CGU46_RS31640 (CGU46_31640)	-	6581997..6582530 (+)	534	WP_003091165.1	DUF2062 domain-containing protein	-
CGU46_RS31645 (CGU46_31645)	-	6582606..6583850 (-)	1245	WP_003105198.1	lipoprotein-releasing ABC transporter permease subunit	-
CGU46_RS31650 (CGU46_31650)	lolD	6583920..6584603 (-)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
CGU46_RS31655 (CGU46_31655)	-	6584596..6585846 (-)	1251	WP_015502671.1	lipoprotein-releasing ABC transporter permease subunit	-
CGU46_RS31660 (CGU46_31660)	-	6585949..6586548 (+)	600	WP_003091172.1	PilZ domain-containing protein	-
CGU46_RS31665 (CGU46_31665)	-	6586558..6586866 (+)	309	WP_021265003.1	hypothetical protein	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79964.54 Da
• Isoelectric Point: 10.5155

>NTDB_id=240267 CGU46_RS31635 WP_023100928.1 6579641..6581866(-) (comA) [Pseudomonas aeruginosa strain Ocean-1175]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLGTLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHALLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPGWLVSGEPARLPSPLFADSCDERRWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=240267 CGU46_RS31635 WP_023100928.1 6579641..6581866(-) (comA) [Pseudomonas aeruginosa strain Ocean-1175]
ATGCGCCTGGGATTGCCAGCTCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCACGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCAGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCTTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGTGCTTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGGAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCTGGGAGCCTGCTGCTATGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCACTTGGCCTGCTGGCGGGCCTGGCCGAGGCGTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCGTTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGGGAGCATGCCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGGTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGCGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCGCAGGCCGGCG
ACAGCAACGACCGCTCCTGCGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCGCGGGTCGACTGGTTGCTGGCGCCGCATCACGGCAGCCGCAGCTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAACGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A509JMW0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	59.223	97.301	0.576
comA	Ralstonia pseudosolanacearum GMI1000	35.742	100	0.367