Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   TRNA_RS29080 Genome accession   NC_006270
Coordinates   1498426..1500522 (-) Length   698 a.a.
NCBI ID   WP_011197893.1    Uniprot ID   Q65KI8
Organism   Bacillus licheniformis DSM 13 = ATCC 14580     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1493426..1505522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TRNA_RS29050 (BL03636) - 1493571..1493900 (-) 330 WP_011197892.1 YkvA family protein -
  TRNA_RS29055 (BL03543) - 1494119..1494361 (+) 243 WP_003181085.1 aspartyl-phosphate phosphatase Spo0E family protein -
  TRNA_RS29060 (BL03637) - 1494423..1495934 (-) 1512 WP_003181087.1 PAS domain-containing sensor histidine kinase -
  TRNA_RS29065 (BL03544) - 1496172..1496627 (+) 456 WP_003181089.1 MarR family winged helix-turn-helix transcriptional regulator -
  TRNA_RS29070 (BL03638) motB 1496652..1497431 (-) 780 WP_003181091.1 flagellar motor protein MotB -
  TRNA_RS29075 (BL03639) motA 1497424..1498227 (-) 804 WP_003181093.1 flagellar motor stator protein MotA -
  TRNA_RS29080 (BL03640) clpE 1498426..1500522 (-) 2097 WP_011197893.1 ATP-dependent protease ATP-binding subunit ClpE Regulator
  TRNA_RS29085 (BL03545) - 1500743..1501777 (+) 1035 WP_003181096.1 hypothetical protein -
  TRNA_RS29090 (BL03546) queC 1502042..1502701 (+) 660 WP_003181098.1 7-cyano-7-deazaguanine synthase QueC -
  TRNA_RS29095 (BL03547) queD 1502704..1503144 (+) 441 WP_003181100.1 6-carboxytetrahydropterin synthase QueD -
  TRNA_RS29100 (BL03548) queE 1503137..1503868 (+) 732 WP_003181103.1 7-carboxy-7-deazaguanine synthase QueE -
  TRNA_RS29105 (BL03549) queF 1503890..1504387 (+) 498 WP_009328607.1 preQ(1) synthase -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78099.23 Da        Isoelectric Point: 5.6308

>NTDB_id=23887 TRNA_RS29080 WP_011197893.1 1498426..1500522(-) (clpE) [Bacillus licheniformis DSM 13 = ATCC 14580]
MRCQHCQKNEATIRLNMQINFTKKQMDLCEDCYKELTQPSMFSGNHFFGGGGSFFSQPSQAQTQTAAKKGLLDELAVNLT
NAAKTGLIDPVIGRDDEVARVIEILNRRNKNNPVLIGEPGVGKTAVAEGLALKIAEGDVPNKLKNKELYLLDVASLVANT
GIRGQFEERMKQLMKELKERKNAILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVIGATTLKEYRQIEKDAALER
RFQPIMVHEPTIEQAAAILNGLKEKYEAYHDVTYTDEAIKACVILSSRYIQDRHLPDKAIDLLDEAGSKANLKIDTVSGE
QASQRLQEIEAEKAKALQEENYELAAKLRDEEEALHKKMESHEEEKRATVEAEDIQAIIEQKTGIPVGKLQHDDQKKMKE
LEAHLSSRVIGQKEAVKKVAKAVRRSRAGLKSKNRPVGSFLFVGPTGVGKTELSKRLAEELFGTKDAIIRLDMSEYMEKH
AVSKLIGSPPGYVGHEEAGQLTEKVRRNPYSIVLLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSNAG
VSEKRTTVGFNREEQVMGEQSMIDSLSGYFKPEFLNRFDSIIEFQPLEKEDLVKIAALLLKELEETLKEQNMTLEVSDEA
KEKIAEIGYHPAFGARPLRRTIQTAVEDQMTDLLLEEEHIKGFAVIVENDEIRVKTTR

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=23887 TRNA_RS29080 WP_011197893.1 1498426..1500522(-) (clpE) [Bacillus licheniformis DSM 13 = ATCC 14580]
ATGCGTTGTCAACATTGTCAAAAAAATGAGGCGACGATTCGCCTAAACATGCAAATCAACTTTACAAAAAAACAAATGGA
TTTATGTGAAGACTGCTATAAAGAGCTGACTCAGCCTTCTATGTTTTCAGGAAATCACTTTTTTGGCGGCGGAGGTTCTT
TCTTCAGCCAGCCATCACAAGCGCAGACGCAAACCGCTGCCAAAAAAGGCTTGCTCGATGAACTTGCCGTCAATTTAACA
AATGCAGCAAAGACCGGCTTGATCGATCCGGTGATCGGCCGCGATGATGAAGTAGCCCGTGTGATCGAGATCTTAAACCG
CAGAAATAAAAACAATCCGGTCTTAATCGGTGAACCGGGCGTCGGTAAAACAGCCGTCGCTGAAGGACTTGCTCTCAAAA
TCGCCGAAGGCGATGTTCCAAATAAATTGAAAAACAAAGAGCTCTACCTGCTTGATGTCGCTTCCCTCGTGGCAAACACC
GGCATCAGAGGGCAATTTGAAGAAAGAATGAAACAGCTGATGAAAGAGCTGAAAGAACGCAAAAACGCAATCTTGTTTAT
TGACGAAATTCACCTTCTTGTCGGGGCCGGCTCTGCAGAAGGCTCCATGGATGCGGGCAACATTTTAAAACCTGCACTTG
CCAGAGGCGAGCTGCAAGTTATCGGCGCTACGACGTTGAAGGAATATCGCCAAATTGAAAAAGATGCGGCGTTAGAGCGG
CGCTTTCAGCCGATCATGGTGCACGAACCGACAATTGAGCAGGCCGCAGCGATTTTAAACGGGCTCAAGGAAAAATACGA
AGCATATCACGATGTGACTTACACGGATGAAGCGATCAAAGCCTGCGTCATTCTGTCAAGCCGCTATATTCAGGACCGCC
ATCTTCCCGATAAGGCGATCGACCTTTTGGATGAAGCCGGTTCAAAAGCGAACTTGAAAATCGACACGGTCAGCGGTGAA
CAAGCTTCCCAACGCCTGCAAGAAATCGAAGCGGAAAAAGCCAAAGCGCTTCAAGAAGAAAACTACGAGCTTGCAGCAAA
ACTCCGCGACGAAGAAGAAGCGCTGCATAAAAAAATGGAAAGCCATGAGGAAGAAAAACGGGCAACAGTTGAAGCGGAAG
ACATTCAAGCGATCATCGAACAAAAAACCGGCATTCCGGTCGGCAAGCTTCAGCACGACGATCAGAAGAAAATGAAAGAG
CTTGAAGCACACCTTTCAAGCCGCGTGATCGGTCAAAAAGAAGCGGTGAAAAAAGTGGCAAAAGCCGTCAGAAGAAGCCG
CGCCGGCCTGAAATCAAAAAACAGGCCTGTCGGTTCATTCCTGTTCGTCGGCCCGACAGGTGTCGGTAAAACAGAACTTT
CTAAAAGGCTTGCGGAAGAACTGTTCGGCACGAAGGATGCCATCATCCGCCTCGATATGAGCGAATACATGGAAAAACAC
GCCGTATCAAAGCTGATCGGTTCGCCTCCTGGATATGTCGGCCACGAAGAAGCCGGACAGCTTACCGAAAAAGTCCGGAG
GAACCCGTACAGCATCGTTTTGCTCGATGAAATCGAAAAAGCCCATCCCGATGTCCAGCACATGTTCCTGCAAATCATGG
AAGACGGACGTCTGACAGACAGCCAAGGGCGGACGGTCAGCTTTAAAGATACCGTCATTATTATGACAAGCAATGCCGGT
GTATCTGAAAAGCGGACAACCGTCGGTTTTAACCGGGAAGAGCAAGTAATGGGCGAACAATCAATGATCGATTCATTAAG
CGGCTACTTTAAGCCGGAATTCCTGAACAGATTTGACAGCATCATCGAATTCCAGCCGCTCGAAAAAGAAGATCTGGTCA
AGATCGCCGCCCTCTTGCTGAAAGAGCTTGAAGAAACGTTAAAAGAGCAAAACATGACGCTCGAAGTTTCAGATGAGGCA
AAAGAAAAAATCGCTGAAATCGGATACCATCCGGCCTTTGGCGCCCGCCCATTAAGAAGAACCATTCAAACAGCGGTCGA
AGATCAAATGACCGATCTGCTGCTTGAAGAAGAACACATCAAAGGTTTTGCGGTTATCGTTGAAAACGATGAAATCCGGG
TGAAAACAACCAGATAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(435-601)

ATPase family associated with various cellular activities (AAA) (AAA)

(114-245)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(607-682)

AAA lid domain (AAA_lid_9)

(252-350)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q65KI8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

56.283

100

0.603
  clpE Streptococcus pneumoniae TIGR4

55.615

100

0.596
  clpE Streptococcus pneumoniae Rx1

55.615

100

0.596
  clpE Streptococcus pneumoniae D39

55.615

100

0.596
  clpE Streptococcus pneumoniae R6

55.615

100

0.596
  clpC Lactococcus lactis subsp. cremoris KW2

55.586

100

0.585
  clpC Bacillus subtilis subsp. subtilis str. 168

53.916

95.129

0.513
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.68

89.542

0.427
  clpC Streptococcus thermophilus LMD-9

46.384

91.117

0.423
  clpC Streptococcus thermophilus LMG 18311

46.372

90.831

0.421
  clpC Streptococcus pneumoniae TIGR4

47.03

89.255

0.42
  clpC Streptococcus pneumoniae Rx1

47.03

89.255

0.42
  clpC Streptococcus pneumoniae D39

47.03

89.255

0.42
  clpC Streptococcus mutans UA159

46.916

88.252

0.414
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

42.834

86.963

0.372

Multiple sequence alignment