Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   C7K40_RS06040 Genome accession   NZ_CP027771
Coordinates   1191215..1191877 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain DMG1800716     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1186215..1196877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7K40_RS06015 (C7K40_06010) - 1186552..1186800 (-) 249 WP_002989183.1 serine hydrolase -
  C7K40_RS06020 (C7K40_06015) - 1186856..1187011 (-) 156 WP_002989180.1 hypothetical protein -
  C7K40_RS06025 (C7K40_06020) sodA 1187178..1187783 (-) 606 WP_002983977.1 superoxide dismutase SodA -
  C7K40_RS06030 (C7K40_06025) holA 1187880..1188920 (-) 1041 WP_023612792.1 DNA polymerase III subunit delta -
  C7K40_RS06035 (C7K40_06030) comEC/celB 1188991..1191234 (-) 2244 WP_023079940.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  C7K40_RS06040 (C7K40_06035) comEA/celA/cilE 1191215..1191877 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  C7K40_RS06045 (C7K40_06040) - 1192077..1192817 (-) 741 WP_012560804.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  C7K40_RS06050 (C7K40_06045) - 1192935..1193711 (+) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  C7K40_RS06055 (C7K40_06050) - 1193701..1193979 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  C7K40_RS06060 (C7K40_06055) - 1194003..1196003 (-) 2001 WP_023612776.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=237197 C7K40_RS06040 WP_002995626.1 1191215..1191877(-) (comEA/celA/cilE) [Streptococcus pyogenes strain DMG1800716]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=237197 C7K40_RS06040 WP_002995626.1 1191215..1191877(-) (comEA/celA/cilE) [Streptococcus pyogenes strain DMG1800716]
ATGTTAGATGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405

Multiple sequence alignment