Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AX062_RS24405 Genome accession   NZ_CP027390
Coordinates   4467349..4467981 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2015C-4944     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4462349..4472981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AX062_RS24380 yhfG 4462481..4462648 (+) 168 WP_000736860.1 YhfG family protein -
  AX062_RS24385 fic 4462638..4463240 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AX062_RS24390 pabA 4463272..4463835 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  AX062_RS24395 argD 4463921..4465141 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AX062_RS24400 yhfK 4465208..4467298 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AX062_RS24405 crp 4467349..4467981 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AX062_RS24415 yhfA 4468283..4468687 (+) 405 WP_001148908.1 OsmC family protein -
  AX062_RS24420 prkB 4468742..4469611 (-) 870 WP_001274680.1 phosphoribulokinase -
  AX062_RS24425 yheU 4469665..4469883 (-) 219 WP_000907085.1 YheU family protein -
  AX062_RS24430 yheT 4469877..4470899 (-) 1023 WP_000057356.1 hydrolase -
  AX062_RS24435 yheS 4470899..4472812 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=233516 AX062_RS24405 WP_000242755.1 4467349..4467981(-) (crp) [Escherichia coli strain 2015C-4944]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=233516 AX062_RS24405 WP_000242755.1 4467349..4467981(-) (crp) [Escherichia coli strain 2015C-4944]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment