Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6N22_RS08810 Genome accession   NZ_CP027310
Coordinates   1744017..1744649 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-4135     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1739017..1749649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6N22_RS08785 yhfG 1739149..1739316 (+) 168 WP_000736860.1 YhfG family protein -
  C6N22_RS08790 fic 1739306..1739908 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6N22_RS08795 pabA 1739940..1740503 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C6N22_RS08800 argD 1740589..1741809 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6N22_RS08805 yhfK 1741876..1743966 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6N22_RS08810 crp 1744017..1744649 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6N22_RS08820 yhfA 1744951..1745355 (+) 405 WP_001148908.1 OsmC family protein -
  C6N22_RS08825 prkB 1745410..1746279 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6N22_RS08830 yheU 1746333..1746550 (-) 218 Protein_1607 YheU family protein -
  C6N22_RS08835 yheT 1746544..1747565 (-) 1022 Protein_1608 hydrolase -
  C6N22_RS08840 yheS 1747565..1749477 (-) 1913 Protein_1609 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=231822 C6N22_RS08810 WP_000242755.1 1744017..1744649(-) (crp) [Escherichia coli strain 2014C-4135]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=231822 C6N22_RS08810 WP_000242755.1 1744017..1744649(-) (crp) [Escherichia coli strain 2014C-4135]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment