Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C5099_RS22320 Genome accession   NZ_CP027103
Coordinates   4277086..4277718 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain RM14723     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4272086..4282718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5099_RS22290 (C5099_22280) yheS 4272256..4274169 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C5099_RS22295 (C5099_22285) yheT 4274169..4275190 (+) 1022 Protein_4117 hydrolase -
  C5099_RS22300 (C5099_22290) yheU 4275184..4275402 (+) 219 WP_000907085.1 YheU family protein -
  C5099_RS22305 (C5099_22295) prkB 4275456..4276325 (+) 870 WP_001274684.1 phosphoribulokinase -
  C5099_RS22310 (C5099_22300) yhfA 4276380..4276784 (-) 405 WP_001148908.1 OsmC family protein -
  C5099_RS22320 (C5099_22310) crp 4277086..4277718 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C5099_RS22325 (C5099_22315) yhfK 4277769..4279859 (+) 2091 WP_001356893.1 YccS/YhfK family putative transporter -
  C5099_RS22330 (C5099_22320) argD 4279937..4281157 (-) 1221 WP_001356894.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C5099_RS22335 (C5099_22325) pabA 4281243..4281806 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  C5099_RS22340 (C5099_22330) fic 4281838..4282440 (-) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  C5099_RS22345 (C5099_22335) yhfG 4282430..4282597 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=230071 C5099_RS22320 WP_000242755.1 4277086..4277718(+) (crp) [Escherichia coli strain RM14723]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=230071 C5099_RS22320 WP_000242755.1 4277086..4277718(+) (crp) [Escherichia coli strain RM14723]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment