Detailed information NTG0229541

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: CA929_RS05125
• Genome accession: NZ_CP021277
• Coordinates: 1081987..1084719 (-)
• Length: 910 a.a.
• NCBI ID: WP_027227781.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. fraseri strain D-4058
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1076987..1089719

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CA929_RS05100	-	1077512..1078933 (-)	1422	WP_027227777.1	APC family permease	-
CA929_RS05105	-	1079008..1079325 (-)	318	WP_010947633.1	BolA/IbaG family iron-sulfur metabolism protein	-
CA929_RS05110	pilA2	1079629..1080039 (+)	411	WP_027227778.1	pilin	Machinery gene
CA929_RS05115	pilA2	1080236..1080649 (+)	414	WP_027227779.1	pilin	Machinery gene
CA929_RS05120	-	1080646..1081890 (-)	1245	WP_027227780.1	6-phosphofructokinase	-
CA929_RS05125	letS	1081987..1084719 (-)	2733	WP_027227781.1	two-component system sensor histidine kinase LetS	Regulator
CA929_RS05130	gltX	1084818..1086230 (+)	1413	WP_027227782.1	glutamate--tRNA ligase	-
CA929_RS05135	-	1086478..1087740 (+)	1263	WP_027227783.1	serine hydrolase domain-containing protein	-
CA929_RS05140	-	1087781..1088776 (+)	996	WP_027227784.1	hypothetical protein	-
CA929_RS05145	gstA	1088973..1089578 (+)	606	WP_027227785.1	glutathione transferase GstA	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 102931.35 Da
• Isoelectric Point: 7.5435

>NTDB_id=229541 CA929_RS05125 WP_027227781.1 1081987..1084719(-) (letS) [Legionella pneumophila subsp. fraseri strain D-4058]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDYTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKEPSTPKIFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDVRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISPEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLVAYEIEKNQTHRFAHLKIICFDDNPLHLEAMSNG
LGFWGIEAIRVDSFNKLSRTLTKHKDCKIAFINVNQGCERQAAELIAKHKQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQTEKNTNQELDTLREQLRFLHPEILIAEDNPVNKMLLTSLLNNNANITTVDDGEMAVTACEDKKFD
MILLDLHMPKLNGLEAAKMIHQKSLMNKHSPIVLITASSSDLSSIDMKKSGVDFCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNREEFIGLMHQKNVKGLADLAHKLHGACCFCGVPILQKRVAQLEKLARRT
ANADNLSEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=229541 CA929_RS05125 WP_027227781.1 1081987..1084719(-) (letS) [Legionella pneumophila subsp. fraseri strain D-4058]
ATGTTGAAAAGTATTGGTATTAAATATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTCGCCTTGCTTTTTGC
TTTTTTTTATAACGGCCTATTTGGTAAAGATCTAAAGCAGCATATGTCCAGACTGGGTGAAGCCTATATTAGGCAATTAC
TTCCAGCAGCCCAGTATGCCATGCTTCGCAATGATTACCGTACATTGCAGGGTTTAATCAATGCCTCAACCATTAACCCG
GAGGTAAAAGCTTTGGCATTTTATAATGCCGATGGCCGATTAATTGCTTATCGTGGCGGCAAGCACTCTATCCATAAACC
ATTCAATCCACCTGACTATACAGGTGACTACATTGAAAGTAAGCAAATTAATCCATTCACCATTAATTTTATAGCGCCGA
TTACTATCCCAAAGTTCAATTTGTACTCAAGCACAGAATTCAAAGAGCCTTCTACGCCTAAAATATTCCAGGCTGACGAT
ATATTAGGCTGGTTATCCATTGACATTGATACACAATCACTACTTATAAAACGCTATCAAATGCTCATCGTTACCATTTT
TATTACTCTATTCGGTTTACTGATGGGTTTAACAATTCATTACTTCTTGTCTAAACGAATTTACATGCCTATTGCTCGAT
TGCGTCGAAGTATGAAGCAAATTTTAAGCAATGAATTCGAAACTGAAATTCGTGTTTCAAGTCCAGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTACAACGACAATATTTAAATACAGTTCGTGATTTGAATCATCACATTGAAATCGCCAC
AGCAGATCTGCAACAAAGTCTCGAACTTCTGGAAGAAAAAAACATTGAGCTATCACTGGAAAAGAAAAAAACTGAAGAAA
AAAGTCGACAAAAATCAGAATTTATTGCCAACATGAGTCATGAAATTCGCACCCCAATGAATGGCGTGATTGGTTTTACA
AATGTTTTATTGGAAAGCAAGCTGGACCCTTTACAACTGGACTACGTTAAAACGATCAAATCATCAGCGCAGGATTTGTT
AAGTATCATCAATGATATTCTGGATTTTTCTAAAATTGATGCGGGCAAATTAAATCTTGATTGCATCCCGCTAGACGTAA
GAGGTTGCATTGATGAGGTTTTATCCCTGGCAAGCCCCAATGCGCACAAAAAAGGAATCGATTTAATCCCGATTACAGAC
ATCAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAACAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACAGATCATGGATACGTTCTTATACGCACTAAAATCGAGCAAGAAACAGATAAAGATTATACCTTACTATTTGCTA
TTACGGATACGGGAATAGGCATTTCACCAGAGGATCAAACGAAACTGTTTACTGCCTTCAATCAGGCAGACACCAGCATC
ACACGCCGTTACGGTGGCTCAGGATTAGGCTTGGTTATATGTAAAAAACTATGTGAAGAAATGCATGGACGTATTAGTCT
AACCAGTGAAATCAACAAAGGCTCTACTTTTAGCGCACGCATTAAAGTTGAAAAACTTGTGGCTTATGAGATTGAAAAAA
ATCAAACTCATCGCTTCGCCCATTTAAAAATCATTTGCTTTGATGACAATCCCCTCCATTTGGAAGCAATGAGTAATGGC
CTAGGATTTTGGGGTATAGAGGCTATACGCGTTGACTCATTTAATAAACTTTCCCGAACATTGACAAAACATAAAGATTG
CAAAATTGCCTTTATTAACGTCAACCAAGGATGTGAGCGACAAGCTGCTGAACTCATTGCCAAACACAAGCAAATTCCTT
TCGTGTTAATTTCTAAATGGCCTATTAATGATTTTGCGGCGCTTGGTGCTCGGGGTTTTCTTTACAAACCTATCAGCATC
CAAAAGCTTCAGGATCTGATTGAATCGATAGCCAATGAAAATCAAACTGAGAAAAATACGAACCAGGAACTGGATACTTT
ACGGGAACAGCTTCGTTTTCTTCATCCAGAGATACTGATTGCAGAAGACAACCCTGTCAATAAAATGCTATTAACATCCC
TATTAAACAATAATGCCAATATAACCACGGTTGACGATGGCGAAATGGCCGTTACTGCTTGTGAGGATAAAAAATTTGAC
ATGATTTTACTGGATCTGCATATGCCCAAACTTAATGGTTTGGAAGCAGCCAAAATGATACATCAAAAATCCCTAATGAA
TAAACACTCTCCTATCGTTCTCATTACCGCCAGTAGCAGTGATCTGAGCTCCATCGATATGAAAAAATCTGGAGTTGATT
TTTGTTTTCAAAAACCTATAGATGAAAAGCAATTGTTAATCCAAATTCTTCGCATCGTTGATAAAACCAAACATGCTGCC
ATTGATTGGCAATTATGCGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTTATAGAAGA
ATTATATAAGAATCGTGAAGAGTTTATTGGGTTAATGCATCAAAAAAACGTAAAGGGCTTGGCTGATTTAGCTCATAAAT
TACATGGCGCCTGTTGTTTTTGTGGCGTGCCTATTTTACAAAAGAGAGTAGCTCAATTAGAGAAGCTTGCAAGACGAACA
GCTAATGCTGATAATTTAAGCGAAGCCTTTACCGATTTAATACAAAGTATTGATGCGGTGATTAGTGAATATGAAAATCA
GTACTCACAATAA

Domains

Predicted by InterproScan.

• Hpt domain (Hpt) (819-900)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• Response regulator receiver domain (Response_reg) (678-787)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Single cache domain 4 (sCache_4) (36-180)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	99.011	100	0.99