Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C4J63_RS02885 Genome accession   NZ_CP026612
Coordinates   531949..532581 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain DTU-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 526949..537581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C4J63_RS02855 (C4J63_02855) yheS 527118..529031 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C4J63_RS02860 (C4J63_02860) yheT 529031..530053 (+) 1023 WP_000057356.1 hydrolase -
  C4J63_RS02865 (C4J63_02865) yheU 530047..530265 (+) 219 WP_000907085.1 YheU family protein -
  C4J63_RS02870 (C4J63_02870) prkB 530319..531188 (+) 870 WP_001274680.1 phosphoribulokinase -
  C4J63_RS02875 (C4J63_02875) yhfA 531243..531647 (-) 405 WP_001148908.1 OsmC family protein -
  C4J63_RS02885 (C4J63_02885) crp 531949..532581 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C4J63_RS02890 (C4J63_02890) yhfK 532632..534722 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C4J63_RS02895 (C4J63_02895) argD 534789..536009 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C4J63_RS02900 (C4J63_02900) pabA 536095..536658 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C4J63_RS02905 (C4J63_02905) fic 536690..537292 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C4J63_RS02910 (C4J63_02910) yhfG 537282..537449 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=227531 C4J63_RS02885 WP_000242755.1 531949..532581(+) (crp) [Escherichia coli strain DTU-1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=227531 C4J63_RS02885 WP_000242755.1 531949..532581(+) (crp) [Escherichia coli strain DTU-1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467