Detailed information NTG0225650

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: B7437_RS14025
• Genome accession: NZ_CP020741
• Coordinates: 2728179..2729066 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143422.1
• Uniprot ID: A0AB73JC73
• Organism: Staphylococcus aureus strain HZW450
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2723179..2734066

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B7437_RS13990 (B7437_14130)	-	2723188..2723280 (+)	93	WP_010956583.1	hypothetical protein	-
B7437_RS13995 (B7437_14135)	-	2723388..2723885 (-)	498	WP_001065268.1	glutathione peroxidase	-
B7437_RS14000 (B7437_14140)	-	2723895..2724155 (-)	261	WP_011382405.1	hypothetical protein	-
B7437_RS14010 (B7437_14150)	-	2724537..2724650 (-)	114	WP_078065157.1	hypothetical protein	-
B7437_RS14015 (B7437_14155)	-	2725319..2727319 (-)	2001	WP_000776726.1	ABC transporter permease	-
B7437_RS14020 (B7437_14160)	-	2727316..2728071 (-)	756	WP_000923775.1	ABC transporter ATP-binding protein	-
B7437_RS14025 (B7437_14165)	braS	2728179..2729066 (-)	888	WP_000143422.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
B7437_RS14030 (B7437_14170)	braR	2729077..2729742 (-)	666	WP_000697884.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
B7437_RS14035 (B7437_14175)	-	2729768..2729968 (-)	201	WP_000604725.1	hypothetical protein	-
B7437_RS14040 (B7437_14180)	-	2730166..2731590 (+)	1425	WP_000953738.1	alkaline phosphatase	-
B7437_RS14840 (B7437_14185)	-	2731650..2731751 (-)	102	WP_000731972.1	SE2200 family small protein	-
B7437_RS14050 (B7437_14190)	-	2731873..2732328 (-)	456	WP_000106183.1	MarR family winged helix-turn-helix transcriptional regulator	-
B7437_RS14055 (B7437_14195)	-	2732573..2733334 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34031.29 Da
• Isoelectric Point: 5.8962

>NTDB_id=225650 B7437_RS14025 WP_000143422.1 2728179..2729066(-) (braS) [Staphylococcus aureus strain HZW450]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGVGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=225650 B7437_RS14025 WP_000143422.1 2728179..2729066(-) (braS) [Staphylococcus aureus strain HZW450]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTGTTGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99