Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   B7474_RS12735 Genome accession   NZ_CP020714
Coordinates   2437722..2438291 (+) Length   189 a.a.
NCBI ID   WP_000872876.1    Uniprot ID   -
Organism   Staphylococcus aureus strain K18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2432722..2443291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7474_RS12710 (B7474_12765) cysE 2433935..2434582 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  B7474_RS12715 (B7474_12770) cysS 2434566..2435966 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  B7474_RS12720 (B7474_12775) - 2435959..2436363 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  B7474_RS12725 (B7474_12780) rlmB 2436371..2437117 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  B7474_RS12730 (B7474_12785) - 2437117..2437641 (+) 525 WP_000664738.1 NYN domain-containing protein -
  B7474_RS12735 (B7474_12790) sigH 2437722..2438291 (+) 570 WP_000872876.1 sigma-70 family RNA polymerase sigma factor Regulator
  B7474_RS12740 (B7474_12795) rpmG 2438406..2438549 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  B7474_RS12745 (B7474_12800) secE 2438605..2438787 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  B7474_RS12750 (B7474_12805) nusG 2438800..2439348 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  B7474_RS12755 (B7474_12810) rplK 2439529..2439951 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  B7474_RS12760 (B7474_12815) rplA 2440159..2440851 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  B7474_RS12770 (B7474_12820) rplJ 2441123..2441623 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  B7474_RS12775 (B7474_12825) rplL 2441666..2442034 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  B7474_RS12780 (B7474_12830) - 2442209..2442817 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.96 Da        Isoelectric Point: 9.6015

>NTDB_id=225516 B7474_RS12735 WP_000872876.1 2437722..2438291(+) (sigH) [Staphylococcus aureus strain K18]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=225516 B7474_RS12735 WP_000872876.1 2437722..2438291(+) (sigH) [Staphylococcus aureus strain K18]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

99.471

100

0.995
  sigH Staphylococcus aureus N315

98.413

100

0.984

Multiple sequence alignment