Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   FORC59_RS07970 Genome accession   NZ_CP020354
Coordinates   1598753..1599439 (-) Length   228 a.a.
NCBI ID   WP_001793467.1    Uniprot ID   A0A641AAY3
Organism   Staphylococcus aureus strain FORC59     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1593753..1604439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC59_RS07950 (FORC59_1480) rpsT 1594667..1594918 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  FORC59_RS07955 (FORC59_1481) holA 1594963..1595937 (-) 975 WP_001282568.1 DNA polymerase III subunit delta -
  FORC59_RS07960 (FORC59_1482) comEC 1595994..1598195 (-) 2202 WP_001566670.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FORC59_RS07965 (FORC59_1483) - 1598200..1598661 (-) 462 WP_000439693.1 ComE operon protein 2 -
  FORC59_RS07970 (FORC59_1484) comEA 1598753..1599439 (-) 687 WP_001793467.1 ComEA family DNA-binding protein Machinery gene
  FORC59_RS07975 (FORC59_1485) - 1599479..1600195 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  FORC59_RS07980 (FORC59_1486) rsfS 1600198..1600551 (-) 354 WP_001088022.1 ribosome silencing factor -
  FORC59_RS07985 (FORC59_1487) yqeK 1600552..1601136 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  FORC59_RS07990 (FORC59_1488) nadD 1601126..1601695 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  FORC59_RS07995 (FORC59_1489) yhbY 1601698..1601988 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  FORC59_RS08000 (FORC59_1490) aroE 1601992..1602798 (-) 807 WP_000666748.1 shikimate dehydrogenase -
  FORC59_RS08005 (FORC59_1491) yqeH 1602812..1603912 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25786.50 Da        Isoelectric Point: 9.6753

>NTDB_id=221698 FORC59_RS07970 WP_001793467.1 1598753..1599439(-) (comEA) [Staphylococcus aureus strain FORC59]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDNALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=221698 FORC59_RS07970 WP_001793467.1 1598753..1599439(-) (comEA) [Staphylococcus aureus strain FORC59]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATAATG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641AAY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

100

100

1
  comEA Staphylococcus aureus N315

97.368

100

0.974

Multiple sequence alignment