Detailed information NTG0216472

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: CWQ20_RS01335
• Genome accession: NZ_CP025029
• Coordinates: 214023..214484 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874812.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SGEHI2015-25
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 209023..219484

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWQ20_RS01300 (CWQ20_01300)	-	210638..211003 (+)	366	WP_000285373.1	DUF1033 family protein	-
CWQ20_RS01310 (CWQ20_01310)	comGA	211176..212147 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
CWQ20_RS01315 (CWQ20_01315)	comGB	212041..213084 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
CWQ20_RS01320 (CWQ20_01320)	comGC/cglC	213081..213410 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
CWQ20_RS01325 (CWQ20_01325)	comGD	213385..213798 (+)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
CWQ20_RS01330 (CWQ20_01330)	comGE	213770..214069 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
CWQ20_RS01335 (CWQ20_01335)	comGF	214023..214484 (+)	462	WP_001874812.1	competence type IV pilus minor pilin ComGF	Machinery gene
CWQ20_RS01340 (CWQ20_01340)	comGG	214462..214833 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
CWQ20_RS01345 (CWQ20_01345)	comGH	214948..215922 (+)	975	WP_001008574.1	class I SAM-dependent methyltransferase	Machinery gene
CWQ20_RS01350 (CWQ20_01350)	-	215954..217147 (+)	1194	WP_000047534.1	acetate kinase	-
CWQ20_RS01355 (CWQ20_01355)	-	217299..217505 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
CWQ20_RS11110 (CWQ20_01360)	-	217573..217701 (+)	129	WP_014959723.1	hypothetical protein	-
CWQ20_RS01365 (CWQ20_01365)	-	217742..218197 (+)	456	WP_000905673.1	hypothetical protein	-
CWQ20_RS01370 (CWQ20_01370)	-	218266..218931 (+)	666	WP_000008113.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17875.89 Da
• Isoelectric Point: 9.8392

>NTDB_id=216472 CWQ20_RS01335 WP_001874812.1 214023..214484(+) (comGF) [Streptococcus agalactiae strain SGEHI2015-25]
MKIIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=216472 CWQ20_RS01335 WP_001874812.1 214023..214484(+) (comGF) [Streptococcus agalactiae strain SGEHI2015-25]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373