Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CVT30_RS35920 Genome accession   NZ_CP024989
Coordinates   8128990..8129631 (+) Length   213 a.a.
NCBI ID   WP_093788510.1    Uniprot ID   A0A919GSV7
Organism   Streptomyces sp. AMCC400023     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8123990..8134631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVT30_RS35900 (CVT30_36185) - 8124819..8125487 (-) 669 WP_045560787.1 transglycosylase SLT domain-containing protein -
  CVT30_RS35905 (CVT30_36190) - 8125793..8126890 (-) 1098 WP_237310858.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  CVT30_RS35910 (CVT30_36195) - 8126887..8127582 (-) 696 WP_193382202.1 SDR family oxidoreductase -
  CVT30_RS35915 (CVT30_36200) - 8127852..8128997 (+) 1146 WP_045560785.1 GAF domain-containing sensor histidine kinase -
  CVT30_RS35920 (CVT30_36205) vraR 8128990..8129631 (+) 642 WP_093788510.1 response regulator transcription factor Regulator
  CVT30_RS35925 (CVT30_36210) chpE 8129789..8130037 (+) 249 WP_033529228.1 chaplin ChpE -
  CVT30_RS35930 (CVT30_36215) - 8130248..8130487 (+) 240 WP_193382203.1 chaplin family protein -
  CVT30_RS35935 (CVT30_36220) - 8130726..8131511 (-) 786 WP_045560782.1 hypothetical protein -
  CVT30_RS35940 (CVT30_36225) - 8131661..8132452 (+) 792 WP_045560781.1 ABC transporter ATP-binding protein -
  CVT30_RS35945 (CVT30_36230) - 8132598..8133029 (+) 432 WP_045560780.1 NfeD family protein -
  CVT30_RS35950 (CVT30_36235) - 8133188..8134135 (+) 948 WP_033529233.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22983.22 Da        Isoelectric Point: 5.0048

>NTDB_id=215936 CVT30_RS35920 WP_093788510.1 8128990..8129631(+) (vraR) [Streptomyces sp. AMCC400023]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELRPDVVLMDVKMPGMDGVEALRKLRELDNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVADALLSQEEANSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=215936 CVT30_RS35920 WP_093788510.1 8128990..8129631(+) (vraR) [Streptomyces sp. AMCC400023]
GTGGCTGACGCGATCAAGGTGCTCCTCGTCGACGACCACCAGGTGGTCCGCCGAGGTCTGCGCACCTTCCTGGAGGTGCA
GGACGACATCGAGGTCGTGGGCGAGGCCGCCGACGGCGCCGAAGGGGTCGCCCGCGCCGAGGAGCTCCGGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCCGGCATGGACGGCGTCGAGGCCCTGCGGAAACTCCGCGAACTCGACAACCCCGCGCGC
GTGCTCATCGTCACCAGCTTCACCGAGCAGCGCACGGTCGTCCCCGCCCTGCGCGCCGGCGCCGCCGGATACGTCTACAA
GGACGTGGACCCCGACGCCCTGGCCGGCGCCATCCGCTCGGTGCACGCCGGACACATCCTCCTCCAGCCGGAGGTCGCCG
ACGCCCTGCTGTCCCAGGAGGAGGCCAACTCCGGCCAGGGGAGAGGCGGTTCGCTGACGGAGCGGGAGCGCGAAGTGCTC
GGCCTGATCGCCGACGGCCGCTCCAACCGCGAGATAGCCCGAGCGCTGGTGCTGTCCGAGAAGACGGTGAAGACCCATGT
CTCGAACATCCTCATGAAGCTCGACCTGGCGGACCGGACCCAGGCCGCCCTCTGGGCGGTACGCCATGGTGTGACCGGAT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A919GSV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

47.17

99.531

0.469
  degU Bacillus subtilis subsp. subtilis str. 168

38.914

100

0.404