Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   COG40_RS19300 Genome accession   NZ_CP024275
Coordinates   3675978..3676610 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O6:H16 strain M9682-C1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3670978..3681610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  COG40_RS19270 yheS 3671147..3673060 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  COG40_RS19275 yheT 3673060..3674082 (+) 1023 WP_047608128.1 hydrolase -
  COG40_RS19280 yheU 3674076..3674294 (+) 219 WP_000907085.1 YheU family protein -
  COG40_RS19285 prkB 3674348..3675217 (+) 870 WP_001274680.1 phosphoribulokinase -
  COG40_RS19290 yhfA 3675272..3675676 (-) 405 WP_001148908.1 OsmC family protein -
  COG40_RS19300 crp 3675978..3676610 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  COG40_RS19305 yhfK 3676661..3678751 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  COG40_RS19310 argD 3678818..3680038 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  COG40_RS19315 pabA 3680124..3680687 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  COG40_RS19320 fic 3680719..3681321 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  COG40_RS19325 yhfG 3681311..3681478 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=212536 COG40_RS19300 WP_000242755.1 3675978..3676610(+) (crp) [Escherichia coli O6:H16 strain M9682-C1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=212536 COG40_RS19300 WP_000242755.1 3675978..3676610(+) (crp) [Escherichia coli O6:H16 strain M9682-C1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467