Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A5T63_RS18465 Genome accession   NZ_CP024273
Coordinates   3556158..3556790 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain F9792     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3551158..3561790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A5T63_RS18435 yheS 3551327..3553240 (+) 1914 WP_001613950.1 ABC transporter ATP-binding protein -
  A5T63_RS18440 yheT 3553240..3554262 (+) 1023 WP_000057392.1 hydrolase -
  A5T63_RS18445 yheU 3554256..3554474 (+) 219 WP_000907085.1 YheU family protein -
  A5T63_RS18450 prkB 3554528..3555397 (+) 870 WP_001274680.1 phosphoribulokinase -
  A5T63_RS18455 yhfA 3555452..3555856 (-) 405 WP_001148908.1 OsmC family protein -
  A5T63_RS18465 crp 3556158..3556790 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A5T63_RS18470 yhfK 3556841..3558931 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  A5T63_RS18475 argD 3558998..3560218 (-) 1221 WP_001718947.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A5T63_RS18480 pabA 3560304..3560867 (-) 564 WP_001718948.1 aminodeoxychorismate synthase component 2 -
  A5T63_RS18485 fic 3560899..3561501 (-) 603 WP_001718949.1 putative adenosine monophosphate-protein transferase Fic -
  A5T63_RS18490 yhfG 3561491..3561658 (-) 168 WP_032201336.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=212451 A5T63_RS18465 WP_000242755.1 3556158..3556790(+) (crp) [Escherichia coli strain F9792]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=212451 A5T63_RS18465 WP_000242755.1 3556158..3556790(+) (crp) [Escherichia coli strain F9792]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467