Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CS032_RS03960 Genome accession   NZ_CP024256
Coordinates   455028..455660 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ATCC 43886     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 450028..460660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CS032_RS03930 yheS 450197..452110 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  CS032_RS03935 yheT 452110..453132 (+) 1023 WP_000057356.1 hydrolase -
  CS032_RS03940 yheU 453126..453344 (+) 219 WP_000907085.1 YheU family protein -
  CS032_RS03945 prkB 453398..454267 (+) 870 WP_001274680.1 phosphoribulokinase -
  CS032_RS03950 yhfA 454322..454726 (-) 405 WP_001148908.1 OsmC family protein -
  CS032_RS03960 crp 455028..455660 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CS032_RS03965 yhfK 455711..457801 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CS032_RS03970 argD 457868..459088 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CS032_RS03975 pabA 459174..459737 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CS032_RS03980 fic 459769..460371 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CS032_RS03985 yhfG 460361..460528 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=212003 CS032_RS03960 WP_000242755.1 455028..455660(+) (crp) [Escherichia coli strain ATCC 43886]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=212003 CS032_RS03960 WP_000242755.1 455028..455660(+) (crp) [Escherichia coli strain ATCC 43886]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467