Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CP957_RS02170 Genome accession   NZ_CP023673
Coordinates   429146..429778 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain SMN013SH2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 424146..434778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CP957_RS02145 (CP957_02150) yhfG 424279..424446 (+) 168 WP_000736863.1 YhfG family protein -
  CP957_RS02150 (CP957_02155) fic 424436..425038 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  CP957_RS02155 (CP957_02160) pabA 425070..425633 (+) 564 WP_000601849.1 aminodeoxychorismate synthase component 2 -
  CP957_RS02160 (CP957_02165) argD 425719..426939 (+) 1221 WP_062882667.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CP957_RS02165 (CP957_02170) yhfK 427005..429095 (-) 2091 WP_062882666.1 YccS/YhfK family putative transporter -
  CP957_RS02170 (CP957_02175) crp 429146..429778 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CP957_RS02180 (CP957_02185) yhfA 430080..430484 (+) 405 WP_001148908.1 OsmC family protein -
  CP957_RS02185 (CP957_02190) prkB 430539..431408 (-) 870 WP_062882665.1 phosphoribulokinase -
  CP957_RS02190 (CP957_02195) yheU 431462..431680 (-) 219 WP_000907085.1 YheU family protein -
  CP957_RS02195 (CP957_02200) yheT 431674..432696 (-) 1023 WP_000057379.1 hydrolase -
  CP957_RS02200 (CP957_02205) yheS 432696..434609 (-) 1914 WP_000634790.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=208322 CP957_RS02170 WP_000242755.1 429146..429778(-) (crp) [Escherichia coli strain SMN013SH2]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=208322 CP957_RS02170 WP_000242755.1 429146..429778(-) (crp) [Escherichia coli strain SMN013SH2]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment