Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   Spy49_0604 Genome accession   CP000829
Coordinates   605776..609444 (+) Length   1222 a.a.
NCBI ID   ACI60926.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 600776..614444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_0602c - 601532..602449 (-) 918 ACI60924.1 Conserved hypothetical protein -
  Spy49_0603 rexB 602600..605815 (+) 3216 ACI60925.1 Putative ATP-dependent exonuclease, subunit B Machinery gene
  Spy49_0604 rexA 605776..609444 (+) 3669 ACI60926.1 Putative ATP-dependent exonuclease, subunit A Machinery gene
  Spy49_0605 - 609584..610204 (+) 621 ACI60927.1 Putative ABC transporter -
  Spy49_0606 rpsU 610543..610719 (+) 177 ACI60928.1 SSU ribosomal protein S21p -
  Spy49_0607c mscL 610847..611209 (-) 363 ACI60929.1 Putative large conductance mechanosensitive channel -
  Spy49_0608 dnaG 611339..613153 (+) 1815 ACI60930.1 DNA primase -
  Spy49_0609 rpoD 613162..614271 (+) 1110 ACI60931.1 RNA polymerase sigma factor RpoD -

Sequence

Protein


Download         Length: 1222 a.a.        Molecular weight: 140274.58 Da        Isoelectric Point: 6.3996

>NTDB_id=20256 Spy49_0604 ACI60926.1 605776..609444(+) (rexA) [Streptococcus pyogenes NZ131]
MLFNINEKGEPLVISFAPFLSPEAIKHLQENERCSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILR
GVSIDRLFISTFTVKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQF
RIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAK
TYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIR
DVTGLIPSGNDVTVSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDIAH
FAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKT
EQGKVILLKENFRSQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSE
GISFSEVTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRTINNP
RNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAYPELIHDTLLGKLNVFLKTLKSWRRYAKL
GSLYDLILENFHERFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVATPKQAV
NLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRL
ATLSEEMRLLYVAMTRAEKKVYFIGKASKSKSQEITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIE
DSDLTQESVGRLQTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEPLLEPIGVDII
EKSSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEEVKTALDLKKIESFFCDTSLG
QFFQTYQKHLYREAPFAILKLDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTY
KLPVTKRYLVLMGGGKPEIVEV

Nucleotide


Download         Length: 3669 bp        

>NTDB_id=20256 Spy49_0604 ACI60926.1 605776..609444(+) (rexA) [Streptococcus pyogenes NZ131]
GTGCTTTTTAACATTAATGAGAAAGGAGAGCCACTTGTGATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACA
TTTACAAGAAAACGAAAGGTGCAGTGATCAGTCTCAAAAACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCC
AAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAAAAACCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGA
GGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTTACTGTTAAAGCAGCTACAGAACTGCGTGAACGGATTGAAAACAA
ATTATACTCACAAATTGCTCAAACTACAGATTTTCAAATGAAAGTTTATTTAACAGAACAATTGCAATCTCTTTGTCAAG
CTGATATTGGTACTATGGATGCTTTTGCACAGAAAGTAGTAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTT
CGTATCATGCAGGATAAAGCAGAACAAGATGTTTTAAAGCAAGAGGTGTTTAGCAAACTCTTTAGTGAGTTTATGAATCA
AAAAGAGGCACCGGTGTTTAGGGCTCTTGTGAAAAATTTTTCTGGTAACTGTAAAGACACTTCAGCTTTTAGAGAGTTAG
TTTATACTTGTTATTCTTTTAGCCAATCGACAGAAAATCCAAAGATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAA
ACTTACCAAAGACTTGAAGATATCCCGGATCATGATATTGAACTCTTACTTTTGGCAATGCAAGATACTGCAAATCAGCT
AAGAGATGTGACTGATATGGAAGATTATGGGCAGCTGACTAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAA
CGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATTTTAAATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGA
GATGTGACAGGCCTTATACCATCTGGGAATGATGTTACAGTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCA
AAAATTAAAACAATTTAGGCATTTAGAAACAATTTTAATGTATCAGAAAGACTGTTTTCCTTTATTGGAACAGTTACAAG
ATTTTGTGCTTGCGTTTTCAGAAGCTTATTTAGCTGTCAAAATACAAGAAAGTGCTTTTGAATTTTCAGATATTGCACAC
TTTGCAATCAAAATTTTAGAGGAAAATACGGATATTCGCCAATCCTATCAGCAACACTATCATGAGGTGATGGTTGATGA
ATATCAAGATAACAATCATATGCAAGAGCGACTCCTGACCTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATA
TCAAACAATCGATCTATCGATTTCGGCAAGCCGATCCTCAGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAAACT
GAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTTCGTAGCCAATCAGAGGTGTTAAATGTCAGCAATGCTGTTTTTAG
TCACTTAATGGACGAATCAGTAGGAGACGTCTTATACGATGAGCAACATCAGTTAATAGCAGGTAGTCATGCTCAAACAG
TCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTATATAATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAG
GGTATTTCATTTAGTGAGGTTACAATTGTTGCCAAAGAAATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGA
CATTACGTTACTCGTTTCTTCAAGAACAAGAAATGATATCATTTCTCATACATTCAATCAATATGGTATTCCTATAGTAA
CAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTGAAGTGATGGTTATGTTAGATACATTACGCACCATTAATAACCCA
AGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCACCGATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACT
TCAAAAAGACAATGAGCTAGATAAAGATTGCCTATATGACAAGATACAAAGGGCTGTGATTGGAAGAGGTGCTTATCCTG
AATTGATCCACGATACCTTGCTTGGCAAGTTAAATGTTTTTTTAAAGACGTTGAAAAGCTGGCGTCGATACGCCAAGCTA
GGGTCGTTGTATGACTTGATTTTGGAAAATTTTCATGAACGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGA
ACAAGCACAAGCTAATCTATACGCATTAGCTCTACGTGCTAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTT
TTATTAAAATGATTGATAAGGTACTTGAGACGCAAAATGACTTAGCTGATGTGGAAGTGGCTACTCCTAAACAAGCTGTT
AATTTAATGACCATTCACAAGTCTAAAGGTTTACAATTTCCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAAT
GACAGATATTCATAAATCATTTATTCTGAATCGGCAGCACGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTAC
TTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCATGGAAACCTTACCTTATCAATTGAACAAACAAGAGTTGCGCTTA
GCAACTTTATCAGAAGAAATGCGCTTACTGTATGTTGCTATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGC
TAGTAAGAGCAAAAGTCAAGAAATCACAGATCCTAAAAAGTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTAT
TGACATTCCAAGATTGGCTATTAGCAATAGCAGATATATTTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAA
GATAGTGATTTGACACAAGAGTCAGTCGGACGACTTCAAACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCG
TCAATCAGAAACAATTGCACGGGCTTTAGATATGTTAGAAGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTC
ATTTGCCAACAGTTCGAACGCCTAGCCAACTTAAGGCAACTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATA
GAGAAATCTTCTCGATCGCTATCTGATTTTACTTTGCCACATTTTTCAAAAAAAGCAAAAGTTGAAGCAAGTCATATTGG
ATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTTGTCAAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAG
GAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTGATCTCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGC
CAATTTTTTCAGACTTACCAAAAACACTTGTATCGAGAAGCGCCATTTGCTATTTTAAAACTTGACCCTATCAGTCAAGA
AGAGTATGTCCTACGTGGTATTATAGATGCCTACTTTTTGTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATA
AATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACCAACAACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTAT
AAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATGGGAGGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(42-476)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1058-1209)

UvrD-like helicase C-terminal domain (UvrD_C)

(486-904)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

47.876

100

0.48

Multiple sequence alignment