Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   SPG_2153 Genome accession   CP001015
Coordinates   2045819..2046481 (-) Length   220 a.a.
NCBI ID   ACF55123.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2040819..2051481
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_2148 - 2040970..2041236 (-) 267 ACF54963.1 conserved hypothetical protein -
  SPG_2149 dnaB 2041238..2042590 (-) 1353 ACF55308.1 replicative DNA helicase -
  SPG_2150 rplI 2042633..2043085 (-) 453 ACF55399.1 50S ribosomal protein L9 -
  SPG_2151 - 2043082..2045055 (-) 1974 ACF55723.1 DHH 1 family protein -
  SPG_2152 yfiA 2045191..2045739 (-) 549 ACF55646.1 ribosomal subunit interface protein -
  SPG_2153 comFC/cflB 2045819..2046481 (-) 663 ACF55123.1 competence protein ComF, putative Machinery gene
  SPG_2154 comFA/cflA 2046478..2047776 (-) 1299 ACF56044.1 helicase, putative Machinery gene
  SPG_2155 - 2047832..2048467 (+) 636 ACF55450.1 conserved hypothetical protein -
  SPG_2156 - 2048752..2049672 (+) 921 ACF55358.1 cysteine synthase (O-acetylserine sulfhydrylase) (O-acetylserine (Thiol)-lyase) -
  SPG_2157 - 2049869..2050267 (-) 399 ACF54904.1 IS66-Spn1, transposase -
  SPG_2158 - 2050300..2050545 (+) 246 ACF56817.1 IS630-SpnII, transposase -
  SPG_2159 - 2050686..2051009 (-) 324 ACF55837.1 IS66-Spn1, transposase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25240.11 Da        Isoelectric Point: 7.7116

>NTDB_id=20245 SPG_2153 ACF55123.1 2045819..2046481(-) (comFC/cflB) [Streptococcus pneumoniae G54]
MKCLLCGQTMKTVLTFSSLLLLRNNDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=20245 SPG_2153 ACF55123.1 2045819..2046481(-) (comFC/cflB) [Streptococcus pneumoniae G54]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATAATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment