Detailed information NTG0201934

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: FORC61_RS10310
• Genome accession: NZ_CP022607
• Coordinates: 2000188..2000901 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain FORC_061
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1995188..2005901

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC61_RS10255	-	1996766..1997029 (-)	264	WP_001205732.1	hypothetical protein	-
FORC61_RS10260 (FORC61_1812)	-	1997038..1997298 (-)	261	WP_000291504.1	DUF1108 family protein	-
FORC61_RS10265 (FORC61_1813)	-	1997303..1997605 (-)	303	WP_114967488.1	DUF2482 family protein	-
FORC61_RS10270 (FORC61_1814)	-	1997698..1997859 (-)	162	WP_000066011.1	DUF1270 domain-containing protein	-
FORC61_RS10275 (FORC61_1815)	-	1997856..1998176 (-)	321	WP_001120936.1	DUF771 domain-containing protein	-
FORC61_RS14390	-	1998326..1998424 (-)	99	Protein_1903	hypothetical protein	-
FORC61_RS10285 (FORC61_1817)	-	1998449..1999192 (-)	744	WP_016170552.1	phage antirepressor KilAC domain-containing protein	-
FORC61_RS10290 (FORC61_1818)	-	1999243..1999572 (+)	330	WP_000180411.1	hypothetical protein	-
FORC61_RS10295 (FORC61_1819)	-	1999561..1999776 (-)	216	WP_001025404.1	MW1434 family type I TA system toxin	-
FORC61_RS10300 (FORC61_1820)	-	1999792..2000055 (-)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
FORC61_RS10305	-	2000052..2000225 (-)	174	WP_001801500.1	hypothetical protein	-
FORC61_RS10310 (FORC61_1821)	irvR	2000188..2000901 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
FORC61_RS10315 (FORC61_1822)	-	2000917..2001849 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
FORC61_RS10320 (FORC61_1823)	-	2001855..2002196 (+)	342	WP_031824606.1	hypothetical protein	-
FORC61_RS10325 (FORC61_1824)	-	2002400..2002582 (+)	183	WP_000705248.1	hypothetical protein	-
FORC61_RS10330 (FORC61_1825)	-	2002682..2003146 (+)	465	WP_000825947.1	hypothetical protein	-
FORC61_RS10335 (FORC61_1826)	-	2003205..2004242 (+)	1038	WP_000857184.1	site-specific integrase	-
FORC61_RS10340 (FORC61_1827)	sph	2004293..2005123 (+)	831	Protein_1915	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=201934 FORC61_RS10310 WP_001031454.1 2000188..2000901(+) (irvR) [Staphylococcus aureus strain FORC_061]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=201934 FORC61_RS10310 WP_001031454.1 2000188..2000901(+) (irvR) [Staphylococcus aureus strain FORC_061]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401