Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CGC46_RS22105 Genome accession   NZ_CP022407
Coordinates   4186941..4187573 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O121:H19 strain 16-9255     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4181941..4192573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGC46_RS22080 (CGC46_22140) yhfG 4182073..4182240 (+) 168 WP_000736860.1 YhfG family protein -
  CGC46_RS22085 (CGC46_22145) fic 4182230..4182832 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CGC46_RS22090 (CGC46_22150) pabA 4182864..4183427 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CGC46_RS22095 (CGC46_22155) argD 4183513..4184733 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CGC46_RS22100 (CGC46_22160) yhfK 4184800..4186890 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CGC46_RS22105 (CGC46_22165) crp 4186941..4187573 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CGC46_RS22115 (CGC46_22175) yhfA 4187875..4188279 (+) 405 WP_001148908.1 OsmC family protein -
  CGC46_RS22120 (CGC46_22180) prkB 4188334..4189203 (-) 870 WP_001274680.1 phosphoribulokinase -
  CGC46_RS22125 (CGC46_22185) yheU 4189257..4189475 (-) 219 WP_000907085.1 YheU family protein -
  CGC46_RS22130 (CGC46_22190) yheT 4189469..4190491 (-) 1023 WP_000057359.1 hydrolase -
  CGC46_RS22135 (CGC46_22195) yheS 4190491..4192404 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=200592 CGC46_RS22105 WP_000242755.1 4186941..4187573(-) (crp) [Escherichia coli O121:H19 strain 16-9255]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=200592 CGC46_RS22105 WP_000242755.1 4186941..4187573(-) (crp) [Escherichia coli O121:H19 strain 16-9255]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467