Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CES94_RS02210 Genome accession   NZ_CP022154
Coordinates   448405..449037 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ABWA45     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 443405..454037
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CES94_RS02185 (CES94_02180) yhfG 443538..443705 (+) 168 WP_000736860.1 YhfG family protein -
  CES94_RS02190 (CES94_02185) fic 443695..444297 (+) 603 WP_001549769.1 putative adenosine monophosphate-protein transferase Fic -
  CES94_RS02195 (CES94_02190) pabA 444329..444892 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CES94_RS02200 (CES94_02195) argD 444978..446198 (+) 1221 WP_000963824.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CES94_RS02205 (CES94_02200) yhfK 446264..448354 (-) 2091 WP_001325239.1 YccS/YhfK family putative transporter -
  CES94_RS02210 (CES94_02205) crp 448405..449037 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CES94_RS02220 (CES94_02215) yhfA 449339..449743 (+) 405 WP_001148908.1 OsmC family protein -
  CES94_RS02225 (CES94_02220) prkB 449798..450667 (-) 870 WP_001274680.1 phosphoribulokinase -
  CES94_RS02230 (CES94_02225) yheU 450721..450939 (-) 219 WP_000907085.1 YheU family protein -
  CES94_RS02235 (CES94_02230) yheT 450933..451955 (-) 1023 WP_000057356.1 hydrolase -
  CES94_RS02240 (CES94_02235) yheS 451955..453868 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=199532 CES94_RS02210 WP_000242755.1 448405..449037(-) (crp) [Escherichia coli strain ABWA45]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=199532 CES94_RS02210 WP_000242755.1 448405..449037(-) (crp) [Escherichia coli strain ABWA45]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACCCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467