Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6L34_RS08120 Genome accession   NZ_CP016679
Coordinates   1572360..1575458 (+) Length   1032 a.a.
NCBI ID   WP_079884412.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22740     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1567360..1580458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L34_RS08090 (A6L34_08090) hpaC 1568070..1568570 (-) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  A6L34_RS08095 (A6L34_08095) nadR 1568685..1569125 (-) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6L34_RS08105 (A6L34_08105) - 1569468..1569977 (-) 510 WP_002225670.1 protein disulfide oxidoreductase -
  A6L34_RS08115 (A6L34_08115) apbC 1570342..1571421 (+) 1080 WP_002248347.1 iron-sulfur cluster carrier protein ApbC -
  A6L34_RS08120 (A6L34_08120) pilC 1572360..1575458 (+) 3099 WP_079884412.1 PilC family type IV pilus tip adhesin Machinery gene
  A6L34_RS08130 (A6L34_08130) carA 1577439..1578572 (+) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6L34_RS08135 (A6L34_08135) - 1578618..1578755 (+) 138 WP_002214606.1 VOC family protein -
  A6L34_RS08150 (A6L34_08150) - 1579335..1579724 (+) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6L34_RS13700 - 1579728..1579895 (+) 168 WP_153312129.1 hypothetical protein -

Sequence

Protein


Download         Length: 1032 a.a.        Molecular weight: 113112.62 Da        Isoelectric Point: 9.8243

>NTDB_id=191591 A6L34_RS08120 WP_079884412.1 1572360..1575458(+) (pilC) [Neisseria meningitidis strain M22740]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGGAMAQTHKYAIIMNEGNQPEVKQNGQYSTIKDKDREREYTYHQGTRGGGG
SVSFNNSDELVSRQSGTAVFGTATYLPPYGKVSGFDEKRLTERGNALNWINTTHPGLIGYSYAGVVCRDSTSCPKLVYKT
RFSFDNTGLAKNAGSLDRHPDPSRENSPIYKLKDHPWLGVSFNLGSENTVKNGNSFNKLISSFSEDNNNQTIVSTTEGSP
ISLGDQQREHTAVVYYLNAKLHLLDKKQIQNITDKTVQLGTLRPRVETTGRSWLNFWATWKIEDKGNITVRLDLPEVKAG
RCVNANNPNKSTKAPSPALTAPALWFGPVQNGKAEMYSASVSTYPDSSSSRIFLQNLKRKNDSNRPGRHSLETLTENDIK
SRQPNFTGRQTIIRLDSGVQQIKLQGNEVANFNRNDGKNDTFGIVSEYGLTPDANEWKKVLLPWTVRAFNDDGRFNTVNK
EENNGKPKYSQRYRIRENGNNGNNGKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRK
DIQNTESTLAKELRAFAEKSYVGDRYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKAENGNPTAVSLFDVK
HDNNGKNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKTIDSTDNKTALYVYDLESSGTLIKKIDVPGGKGGLSSP
TLVDKDLDGIVDIAYAGDRGGNMYRFDLSGNNPNSWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNKD
IQHVYGIFDNDTDTGTAQDGQGKGLLEQVLSEENKTLFLTDYKRSNGSGSKGWMVKLQPRQRVTVKPTVVLRTAFVTIRK
YKDNGCGAETAILGINTADGGKLTKKSARPIVPAANQAVAQYSGHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDKPVNVR
YLDEKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3099 bp        

>NTDB_id=191591 A6L34_RS08120 WP_079884412.1 1572360..1575458(+) (pilC) [Neisseria meningitidis strain M22740]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGGGAAACCAGCCCGAGGTAAAGCAGA
ATGGGCAATATTCAACAATAAAGGACAAAGACAGGGAGCGCGAATATACTTATCATCAGGGCACAAGAGGAGGAGGAGGC
TCTGTCTCATTCAACAATAGCGATGAGCTTGTTTCTCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCC
GCCCTACGGCAAGGTTTCCGGTTTTGATGAAAAGAGGCTGACAGAGCGCGGCAATGCCCTTAATTGGATTAATACGACCC
ACCCAGGGTTGATAGGCTACAGCTACGCCGGTGTCGTATGCAGAGACAGCACAAGCTGTCCCAAACTTGTCTATAAAACC
CGATTTTCCTTCGACAACACCGGTTTGGCAAAAAATGCGGGCAGCCTGGATAGGCACCCGGACCCAAGCCGCGAAAATTC
GCCCATTTACAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATGGCA
ACTCATTCAACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAGGCTCCCCT
ATTTCCCTTGGCGACCAGCAGCGCGAACATACCGCCGTGGTCTATTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAA
ACAGATTCAAAATATCACCGACAAAACAGTGCAGTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAAGCTGGC
TAAATTTTTGGGCTACGTGGAAGATTGAAGATAAAGGGAACATTACAGTCCGCCTCGACCTGCCGGAAGTCAAAGCAGGC
CGCTGCGTCAACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACCGCCCCCGCGCTGTGGTTCGG
CCCTGTGCAAAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTTCC
TTCAAAATCTGAAAAGAAAAAACGACTCCAACAGACCCGGCCGCCATTCCCTCGAAACCTTGACTGAGAACGATATTAAA
AGTCGACAGCCGAATTTCACAGGGCGGCAAACAATCATCCGATTGGATAGCGGCGTACAGCAGATCAAACTTCAAGGCAA
TGAGGTCGCCAATTTTAATAGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAATATGGCCTCACGCCTGATG
CCAATGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACAGTCAACAAA
GAAGAAAACAACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAACAACGGCAAGCG
TGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGC
ATATCTTCAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCAAG
GATATTCAAAACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAAGCTATGTGGGCGACCGCTACGG
CGTGGACGGCGGCTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTTG
GCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAGCCGAAAACGGTAACCCGACCGCCGTTTCCCTGTTTGATGTCAAA
CATGACAATAATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCA
CAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACAGCACAGACAATAAAACCGCGCTGT
ATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCC
ACGCTGGTGGATAAAGATTTGGACGGCATTGTTGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGA
TTTAAGCGGCAACAACCCGAACAGTTGGACTGTACGCCCTATTTTTGAAGGCACAAAACCGATTACTTCCGCGCCCGCCA
TTTCCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTGGACAACAAAGAC
ATCCAACACGTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGGGCTGCTCGA
GCAAGTGCTTAGTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCAACGGATCGGGCAGTAAGGGGTGGA
TGGTGAAATTGCAGCCCAGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAA
TATAAAGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAG
CGCGCGCCCGATTGTGCCGGCAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAAATCCA
TCCCTATAGGTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGC
TACCTGGACGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGG
CAAGCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGG
ACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(509-840)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

81.184

100

0.824

Multiple sequence alignment