Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A6J85_RS00765 Genome accession   NZ_CP020450
Coordinates   135748..136380 (-) Length   210 a.a.
NCBI ID   WP_082307132.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 130748..141380
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS00740 (A6J85_00735) comFA/cflA 130824..132125 (-) 1302 WP_082307130.1 DEAD/DEAH box helicase Machinery gene
  A6J85_RS00745 (A6J85_00740) - 132181..132813 (+) 633 WP_045772978.1 YigZ family protein -
  A6J85_RS00750 (A6J85_00745) cysK 132911..133840 (+) 930 WP_061599612.1 cysteine synthase A -
  A6J85_RS00755 (A6J85_00750) - 133874..134260 (-) 387 WP_012000099.1 S1 RNA-binding domain-containing protein -
  A6J85_RS00760 (A6J85_00755) - 134257..135660 (-) 1404 WP_082307131.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  A6J85_RS00765 (A6J85_00760) vraR 135748..136380 (-) 633 WP_082307132.1 response regulator transcription factor Regulator
  A6J85_RS00770 (A6J85_00765) - 136382..137383 (-) 1002 WP_082307133.1 sensor histidine kinase -
  A6J85_RS00775 (A6J85_00770) liaF 137380..138078 (-) 699 WP_045506061.1 cell wall-active antibiotics response protein LiaF -
  A6J85_RS00780 (A6J85_00775) stkP 138251..140104 (-) 1854 WP_045772973.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A6J85_RS00785 (A6J85_00780) - 140101..140841 (-) 741 WP_082307774.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23762.31 Da        Isoelectric Point: 4.8067

>NTDB_id=186590 A6J85_RS00765 WP_082307132.1 135748..136380(-) (vraR) [Streptococcus gordonii strain FDAARGOS_257]
MKILLVDDHEMVRLGLKSYLDLQADVEVVAESSNGREGVEQALELRPDVIIMDIVMPEMNGIEATMAILETWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADEILHAVRKVARGEIAIETEVSKKVQYHRNHIELHDDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=186590 A6J85_RS00765 WP_082307132.1 135748..136380(-) (vraR) [Streptococcus gordonii strain FDAARGOS_257]
ATGAAAATTTTATTAGTAGATGATCACGAAATGGTTCGTTTGGGCTTAAAAAGCTACCTAGACTTACAAGCAGATGTTGA
AGTGGTGGCAGAAAGTTCTAATGGCCGTGAGGGAGTTGAGCAGGCTTTGGAGCTGAGACCAGATGTCATCATCATGGATA
TTGTTATGCCAGAGATGAATGGTATCGAGGCTACTATGGCTATTCTAGAAACTTGGCCAGAGGCAAAAATTTTGATTTTG
ACTTCCTACTTGGATAATGAAAAGATTTATCCTGTTCTGGATGCTGGAGCTAAAGGTTACATGCTGAAGACATCTAGTGC
AGATGAGATCTTACATGCTGTCCGAAAAGTAGCTAGAGGAGAAATTGCGATTGAAACAGAAGTCAGTAAAAAAGTTCAGT
ACCATCGCAATCACATTGAATTACATGATGATTTAACCGCTCGAGAACGAGATATTTTGGGGCTTCTAGCCAAGGGATAT
GAAAATCAACGCATTGCAGATGAGCTTTTTATTTCTCTGAAAACAGTAAAAACTCATGTTTCTAATATCTTGTCAAAATT
GGAAGTGAGTGACCGGACTCAAGCGGTTGTTTATGCCTTTCAGCATCACTTGGTTCCTCAGGAAGACTTCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

98.095

0.533
  degU Bacillus subtilis subsp. subtilis str. 168

40.625

100

0.433

Multiple sequence alignment