Detailed information NTG0186033

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: A9494_RS07980
• Genome accession: NZ_CP016175
• Coordinates: 1568044..1569093 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain LSM102
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1563044..1574093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A9494_RS07960 (A9494_07785)	nadE	1563450..1564274 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
A9494_RS07965 (A9494_07790)	-	1565570..1566097 (-)	528	WP_012027591.1	VanZ family protein	-
A9494_RS07970 (A9494_07795)	rlmN	1566094..1567206 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
A9494_RS07975 (A9494_07800)	-	1567215..1567856 (-)	642	WP_012027595.1	YutD family protein	-
A9494_RS07980 (A9494_07805)	sepM	1568044..1569093 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
A9494_RS07985 (A9494_07810)	coaD	1569080..1569568 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
A9494_RS07990 (A9494_07815)	rsmD	1569558..1570097 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
A9494_RS07995 (A9494_07820)	-	1570405..1571127 (-)	723	WP_012027598.1	lipoprotein	-
A9494_RS08000 (A9494_07825)	-	1571184..1571570 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
A9494_RS08005 (A9494_07830)	-	1571570..1571788 (-)	219	WP_004194736.1	YqgQ family protein	-
A9494_RS08010 (A9494_07835)	-	1572096..1572698 (-)	603	WP_012027601.1	response regulator transcription factor	-
A9494_RS08015 (A9494_07840)	-	1572695..1573789 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=186033 A9494_RS07980 WP_012775295.1 1568044..1569093(-) (sepM) [Streptococcus suis strain LSM102]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=186033 A9494_RS07980 WP_012775295.1 1568044..1569093(-) (sepM) [Streptococcus suis strain LSM102]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605