Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LL158_RS08755 Genome accession   NZ_CP015894
Coordinates   1740977..1741678 (-) Length   233 a.a.
NCBI ID   WP_011676802.1    Uniprot ID   A0A0M2ZUZ8
Organism   Lactococcus cremoris strain 158     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1735977..1746678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL158_RS08735 (LL158_1691) - 1736090..1737307 (-) 1218 WP_014572151.1 cysteine desulfurase -
  LL158_RS08740 (LL158_1692) sufD 1737307..1738563 (-) 1257 WP_015082754.1 Fe-S cluster assembly protein SufD -
  LL158_RS08745 (LL158_1693) sufC 1738703..1739473 (-) 771 WP_011676800.1 Fe-S cluster assembly ATPase SufC -
  LL158_RS08750 (LL158_1694) - 1739649..1740974 (-) 1326 WP_015082755.1 MraY family glycosyltransferase -
  LL158_RS08755 (LL158_1695) mecA 1740977..1741678 (-) 702 WP_011676802.1 adaptor protein MecA Regulator
  LL158_RS08760 (LL158_1696) - 1741807..1742541 (-) 735 WP_011676803.1 amino acid ABC transporter ATP-binding protein -
  LL158_RS08765 (LL158_1697) - 1742541..1743227 (-) 687 WP_015082756.1 amino acid ABC transporter permease -
  LL158_RS08770 (LL158_1698) - 1743373..1744281 (-) 909 WP_015082757.1 diacylglycerol kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27046.46 Da        Isoelectric Point: 4.1802

>NTDB_id=182840 LL158_RS08755 WP_011676802.1 1740977..1741678(-) (mecA) [Lactococcus cremoris strain 158]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGAKKEEAEHEPDFIYYSIRYDDMMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKAKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLITTRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=182840 LL158_RS08755 WP_011676802.1 1740977..1741678(-) (mecA) [Lactococcus cremoris strain 158]
ATGAAGTATGAGGATATAAATGAAAACACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAGTT
ATCTGACTTTTTTGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTAGTTGATGAACTTGGCTTAGAAAATCGTT
TTGGAAATGTAGGGATGTTAACTTTCCAAATTCAACCCTTCCCACAAGGCGTCCATATGATTGTTCATGAAGAAGCAATG
TTGGGTGAAGGCGGAGAGATTCCAGATGATCCTGAAGAATTTGAAGAATTAATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGACTTGGTTTACCAGGGGCTAAAAAAGAAG
AAGCCGAACATGAGCCAGACTTTATATACTACTCTATTCGTTATGATGACATGATGTCTGTCTTGACTGGAATAAAAAAT
GTGAAATTCGCAGATGAAGAGTCAGAATTTTATCGTTATGATGGTAATTTTTATCTTGTTGTTTTAGATAATCAAAAAGC
AAAAGGTAAAATGCATGTTGAAAGCACACGTTCACGGATGATGGAATATGGTGAAGCGACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGCCTAATCACAACGCGTGCTTTAGACGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M2ZUZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

100

100

1
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

96.567

100

0.966

Multiple sequence alignment