Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BE957_RS05450 Genome accession   NZ_CP018948
Coordinates   641572..642204 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain Ecol_224     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 636572..647204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BE957_RS05425 (BE957_05570) yhfG 636704..636871 (+) 168 WP_000736860.1 YhfG family protein -
  BE957_RS05430 (BE957_05575) fic 636861..637463 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  BE957_RS05435 (BE957_05580) pabA 637495..638058 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  BE957_RS05440 (BE957_05585) argD 638144..639364 (+) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  BE957_RS05445 (BE957_05590) yhfK 639431..641521 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  BE957_RS05450 (BE957_05595) crp 641572..642204 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  BE957_RS05460 (BE957_05605) yhfA 642506..642910 (+) 405 WP_001148908.1 OsmC family protein -
  BE957_RS05465 (BE957_05610) prkB 642965..643834 (-) 870 WP_001274680.1 phosphoribulokinase -
  BE957_RS05470 (BE957_05615) yheU 643888..644106 (-) 219 WP_060614994.1 YheU family protein -
  BE957_RS05475 (BE957_05620) yheT 644100..645122 (-) 1023 WP_000057379.1 hydrolase -
  BE957_RS05480 (BE957_05625) yheS 645122..647035 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=176944 BE957_RS05450 WP_000242755.1 641572..642204(-) (crp) [Escherichia coli strain Ecol_224]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=176944 BE957_RS05450 WP_000242755.1 641572..642204(-) (crp) [Escherichia coli strain Ecol_224]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467