Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   A4G25_RS12760 Genome accession   NZ_CP015114
Coordinates   2657625..2658668 (+) Length   347 a.a.
NCBI ID   WP_047132847.1    Uniprot ID   A0A143P7E7
Organism   Staphylococcus condimenti strain DSM 11674     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2652625..2663668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4G25_RS12735 (A4G25_12735) - 2653606..2654331 (+) 726 WP_047132842.1 type 1 glutamine amidotransferase -
  A4G25_RS12740 (A4G25_12740) - 2654381..2655367 (-) 987 WP_047132843.1 FUSC family protein -
  A4G25_RS12745 (A4G25_12745) map 2655615..2656382 (+) 768 WP_047132844.1 type I methionyl aminopeptidase -
  A4G25_RS12750 (A4G25_12750) - 2656516..2656911 (+) 396 WP_047132845.1 hypothetical protein -
  A4G25_RS12755 (A4G25_12755) liaF 2656927..2657628 (+) 702 WP_047132846.1 cell wall-active antibiotics response protein LiaF -
  A4G25_RS12760 (A4G25_12760) vraS 2657625..2658668 (+) 1044 WP_047132847.1 sensor histidine kinase Regulator
  A4G25_RS12765 (A4G25_12765) vraR 2658658..2659287 (+) 630 WP_047132848.1 response regulator transcription factor Regulator
  A4G25_RS13410 - 2659336..2659458 (-) 123 WP_418080431.1 hypothetical protein -
  A4G25_RS13415 - 2659484..2659636 (-) 153 WP_418080432.1 hypothetical protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40101.54 Da        Isoelectric Point: 5.0629

>NTDB_id=176780 A4G25_RS12760 WP_047132847.1 2657625..2658668(+) (vraS) [Staphylococcus condimenti strain DSM 11674]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIVFFQGMFYTQIFGIPVFLFLNIIVILMCIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQNIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=176780 A4G25_RS12760 WP_047132847.1 2657625..2658668(+) (vraS) [Staphylococcus condimenti strain DSM 11674]
ATGAACCATTATATAAGAGCGATAGGTTCAATGTTAATATTGATTTACAGCATTTTAGCTATTTTCTTTTTCATCGATAA
AGTCTTTGTAAATATTGTCTTTTTTCAAGGAATGTTCTATACACAAATTTTCGGAATTCCAGTTTTTTTGTTTTTAAATA
TCATTGTAATATTGATGTGTATTATCGTAGGTTCTGTATTAGCGTATAAAGTGAACCAGCAAAATCATTGGATTAAAGAC
CAAATTGAACATTCTATTGAAGGTGAAGTCGTAGGTATTAATGATCAAAATATCGAACTTTATCAAGAGACGTTAGATAT
CTATCATATGTTGGTACCTTTAAATCAAGAATTGCACCGCTTACGTATTAAAACACAAGATTTAACGAATGAAACTTATA
ATTTAAATGATACAAAAGTAAAAAAAATTATAGAAGATGAACGTCAACGTTTAGCAAGAGAACTGCATGACTCGGTGAGC
CAGCAATTATTTGCTGCAAGTATGATGTTGTCTGCTATAAAGGAAACTAAGTTAGAACCGCCTTTAGATCAACAAATTCC
AACACTTGAAAAGATGGTACAAGATTCACAACTTGAAATGCGTGCTTTATTGCTTCATTTACGTCCATTAGGCTTAAAGG
ACCGTTCATTAGGTGAAGGTATTAAAGACTTGGTTGTAGACTTGCAGAAAAAAGTTCCGATGAAGGTAGTTTATGATATC
GAAGATTTTGAAGTGCCAAAAGGGATAGAAGATCATTTATTCCGAATAACACAAGAAGGTATATCAAACACTTTGCGACA
TGCCGAAGGTACTAAATTGACGATAGATTTATATAATAAAGACGATTATTTACTATTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)

Histidine kinase (HisKA_3)

(147-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A143P7E7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

85.591

100

0.856

Multiple sequence alignment