Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BTR42_RS03050 Genome accession   NZ_CP018822
Coordinates   558850..559494 (+) Length   214 a.a.
NCBI ID   WP_009853571.1    Uniprot ID   A0A060RG88
Organism   Streptococcus gallolyticus subsp. gallolyticus DSM 16831     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 553850..564494
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BTR42_RS03030 (BTR42_02750) - 554424..555161 (+) 738 WP_009853567.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BTR42_RS03035 (BTR42_02755) pknB 555161..557038 (+) 1878 WP_012961536.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  BTR42_RS03040 (BTR42_02760) liaF 557149..557844 (+) 696 WP_009853569.1 cell wall-active antibiotics response protein LiaF -
  BTR42_RS03045 (BTR42_02765) - 557841..558866 (+) 1026 WP_012961538.1 sensor histidine kinase -
  BTR42_RS03050 (BTR42_02770) vraR 558850..559494 (+) 645 WP_009853571.1 response regulator transcription factor Regulator
  BTR42_RS03055 (BTR42_02775) - 559613..561013 (+) 1401 WP_077496363.1 Cof-type HAD-IIB family hydrolase -
  BTR42_RS03060 (BTR42_02780) - 561013..561369 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  BTR42_RS03065 (BTR42_02785) cysK 561483..562412 (-) 930 WP_012961540.1 cysteine synthase A -
  BTR42_RS03070 (BTR42_02790) - 562516..563142 (-) 627 WP_074658787.1 YigZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23939.71 Da        Isoelectric Point: 4.6633

>NTDB_id=176174 BTR42_RS03050 WP_009853571.1 558850..559494(+) (vraR) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
MTQKIKVILVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=176174 BTR42_RS03050 WP_009853571.1 558850..559494(+) (vraR) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
ATGACCCAGAAAATTAAAGTTATCCTAGTTGATGACCATGAAATGGTACGTTTAGGGTTAAAAAGTTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTTGGCGAAGCTGGAAATGGTTTAGATGGTATCAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGCGGTGTCGAAGCAACATTGAAGCTTCTGGAAGAATGGAAGGAAGCTAAA
ATTCTTGTTTTAACATCTTACCTTGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCCATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCTCATGATATGCAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAATCAAACTATTGCTGATGAGCTATTTATCTCACTAAAAACCGTCAAAACACACGTTTCAAATAT
TCTAGCTAAGTTAGAAGTTGATGACCGTACACAAGCAGTCGTTTATGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060RG88

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.427

96.262

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.393