Detailed information NTG0170753

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AYM14_RS14905
• Genome accession: NZ_CP014365
• Coordinates: 2801258..2802145 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300-SUR2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2796258..2807145

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM14_RS14870 (AYM14_14510)	-	2796277..2796369 (+)	93	WP_010956583.1	hypothetical protein	-
AYM14_RS14875 (AYM14_14515)	-	2796477..2796974 (-)	498	WP_001065268.1	glutathione peroxidase	-
AYM14_RS14880 (AYM14_14520)	-	2796984..2797244 (-)	261	WP_001789910.1	hypothetical protein	-
AYM14_RS14890 (AYM14_14525)	-	2797626..2797739 (-)	114	WP_001791776.1	hypothetical protein	-
AYM14_RS14895 (AYM14_14535)	-	2798398..2800398 (-)	2001	WP_000776751.1	ABC transporter permease	-
AYM14_RS14900 (AYM14_14540)	-	2800395..2801150 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AYM14_RS14905 (AYM14_14545)	braS	2801258..2802145 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AYM14_RS14910 (AYM14_14550)	braR	2802156..2802821 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AYM14_RS14915 (AYM14_14555)	-	2802847..2803047 (-)	201	WP_000604728.1	hypothetical protein	-
AYM14_RS14920 (AYM14_14565)	-	2803245..2804669 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AYM14_RS15625	-	2804739..2804849 (+)	111	WP_001791296.1	hypothetical protein	-
AYM14_RS14930 (AYM14_14570)	-	2804952..2805407 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AYM14_RS14935 (AYM14_14575)	-	2805652..2806413 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=170753 AYM14_RS14905 WP_000143419.1 2801258..2802145(-) (braS) [Staphylococcus aureus strain USA300-SUR2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=170753 AYM14_RS14905 WP_000143419.1 2801258..2802145(-) (braS) [Staphylococcus aureus strain USA300-SUR2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997