Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   A4W87_RS06235 Genome accession   NZ_CP017273
Coordinates   1230818..1232701 (-) Length   627 a.a.
NCBI ID   WP_011374401.1    Uniprot ID   Q38XT3
Organism   Latilactobacillus sakei strain TMW 1.1396     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1225818..1237701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4W87_RS06210 (A4W87_06170) - 1227293..1227655 (-) 363 WP_011374405.1 Asp23/Gls24 family envelope stress response protein -
  A4W87_RS06215 (A4W87_06175) rpmB 1227958..1228143 (+) 186 WP_004265581.1 50S ribosomal protein L28 -
  A4W87_RS06220 (A4W87_06180) - 1228496..1229146 (-) 651 WP_011374404.1 thiamine diphosphokinase -
  A4W87_RS06225 (A4W87_06185) rpe 1229133..1229795 (-) 663 WP_011374403.1 ribulose-phosphate 3-epimerase -
  A4W87_RS06230 (A4W87_06190) rsgA 1229819..1230718 (-) 900 WP_011374402.1 ribosome small subunit-dependent GTPase A -
  A4W87_RS06235 (A4W87_06195) pknB 1230818..1232701 (-) 1884 WP_011374401.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A4W87_RS06240 (A4W87_06200) - 1232698..1233444 (-) 747 WP_025015868.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  A4W87_RS06245 (A4W87_06205) rsmB 1233466..1234809 (-) 1344 WP_076632157.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  A4W87_RS06250 (A4W87_06210) fmt 1234799..1235755 (-) 957 WP_076632158.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68176.82 Da        Isoelectric Point: 6.1250

>NTDB_id=167729 A4W87_RS06235 WP_011374401.1 1230818..1232701(-) (pknB) [Latilactobacillus sakei strain TMW 1.1396]
MMETGYAVAGRYKIIRPIGEGGMANVYLAQDLILDRQVAVKVLRLDLRNDPSTVRRFTREALATTELNHPNIVSIYDVGE
ENSMQYIIMEYIKGTDLKKYIVEHFPIPYQRVIDIMTQILSAVQNAHAHNIIHRDLKPQNILVDEDGNIKISDFGIAIAL
SETAMTQTNTLLGSVHYLSPEQARGSMATKRSDIYSLGIVLYELLTGMVPFEGESAVSIAIKHFQDEVPPVRNYDPRIPQ
ALENVVLKATAKDPDERYSGVDAMMADLATSLSASRAHEPKFVPSKADDLSETKVIPALDPEGITQTNNDEEQVKEAEST
QKKVKKPAKSKRKWWLLGGGVVLLLLLATVIAFAVQGSEVTVPDLTDMTQQNAESALTDKKLKVGTVQKTTSQKYSKGHV
IRTTPKAGLSVKSKSTVNLIVSSGRQKYKIKDYTNQAYSDVRDALKDKGLKVKRKYQSSSEVSPGLIIDQSIAAGKRVVP
SKTTITLTVSSGKPGFALHNLSNYTKQGIQDYAAQNGLTVVFSEEYSSSISEGMVISQSPASGTMVQEGDSVSVILSKGE
QPTEHHSIVTSSSNSVIESSAPESSQSSESSASESESESESESESESASESISSSASQSSQSSVQSK

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=167729 A4W87_RS06235 WP_011374401.1 1230818..1232701(-) (pknB) [Latilactobacillus sakei strain TMW 1.1396]
ATGATGGAAACAGGGTACGCTGTAGCGGGGCGTTATAAGATTATTCGGCCCATTGGTGAAGGCGGCATGGCTAATGTTTA
TTTGGCGCAGGATCTAATTTTAGACCGGCAAGTGGCAGTTAAAGTTTTACGATTAGATCTCCGAAATGATCCGAGTACAG
TCCGACGGTTTACGCGAGAAGCGTTGGCAACGACTGAATTAAATCATCCGAATATTGTTAGTATTTACGATGTTGGTGAA
GAAAACAGTATGCAGTACATCATTATGGAATATATTAAGGGCACCGATCTTAAGAAATATATCGTGGAACACTTTCCAAT
TCCTTATCAACGTGTAATTGATATTATGACGCAGATTTTATCTGCGGTTCAAAACGCACATGCGCATAATATTATTCATC
GGGATTTAAAACCACAAAATATTTTGGTTGATGAAGACGGCAATATTAAGATTAGTGACTTTGGGATTGCGATTGCGCTC
AGCGAAACAGCGATGACTCAGACCAACACGTTGTTGGGGTCTGTGCATTATCTCTCACCGGAACAGGCAAGAGGCTCGAT
GGCGACGAAACGGTCTGATATTTACTCGTTAGGAATTGTGCTTTATGAGTTATTGACGGGGATGGTGCCTTTTGAAGGCG
AGTCCGCTGTTTCAATTGCGATTAAGCATTTCCAAGATGAAGTCCCACCAGTACGCAACTATGATCCACGTATTCCGCAA
GCCCTGGAAAATGTCGTTTTAAAAGCGACTGCCAAGGATCCGGATGAACGCTATAGTGGTGTTGATGCCATGATGGCTGA
CTTAGCAACTTCTTTATCAGCTAGTCGTGCGCACGAACCTAAATTTGTGCCATCAAAAGCGGATGATTTGAGTGAGACTA
AGGTGATTCCTGCACTAGATCCAGAAGGCATTACGCAAACCAACAACGATGAGGAACAAGTTAAAGAAGCAGAATCAACT
CAGAAAAAGGTTAAAAAGCCAGCTAAGTCTAAGCGTAAGTGGTGGCTACTAGGTGGCGGTGTTGTTTTATTGCTGTTATT
AGCAACGGTGATTGCTTTTGCAGTTCAGGGGAGCGAAGTAACCGTCCCTGATTTAACGGATATGACACAACAAAATGCGG
AATCTGCTTTGACCGATAAAAAACTGAAAGTCGGCACGGTTCAAAAAACAACGAGTCAGAAATACAGTAAGGGCCACGTC
ATTCGAACAACACCTAAAGCGGGCCTGAGTGTAAAATCAAAAAGTACGGTTAATTTAATTGTCAGTTCAGGACGCCAAAA
GTATAAGATTAAAGACTATACGAACCAAGCATATAGTGATGTTCGGGATGCTTTGAAGGATAAAGGCTTGAAAGTTAAAC
GGAAATACCAAAGTTCATCTGAAGTGAGTCCTGGGTTGATTATCGATCAAAGTATTGCGGCTGGCAAAAGGGTCGTTCCA
AGTAAAACGACGATTACCTTAACAGTCAGCAGCGGTAAACCTGGTTTTGCATTGCATAATCTAAGCAACTATACAAAGCA
AGGGATTCAAGACTATGCTGCACAAAATGGTTTAACGGTCGTATTCTCTGAAGAATATTCATCAAGTATTTCTGAAGGAA
TGGTAATCAGTCAATCGCCTGCAAGTGGTACAATGGTTCAAGAAGGTGATAGCGTAAGCGTTATCCTTTCAAAAGGCGAG
CAACCAACTGAACATCATTCTATTGTGACGTCGAGTTCAAATTCAGTTATCGAGTCGAGTGCGCCTGAATCAAGTCAATC
GAGTGAAAGTAGCGCGAGTGAGTCAGAGAGCGAATCAGAGAGTGAATCGGAAAGCGAATCAGCAAGTGAATCGATCAGTA
GTTCAGCTAGTCAAAGTAGTCAATCGAGCGTTCAATCAAAGTAA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(429-490)

PASTA domain (PASTA)

(500-558)

PASTA domain (PASTA)

(360-422)

Protein kinase domain (Pkinase)

(12-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q38XT3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

42.321

93.461

0.396
  stkP Streptococcus pneumoniae TIGR4

40.304

94.577

0.381
  stkP Streptococcus pneumoniae D39

40.135

94.577

0.38
  stkP Streptococcus pneumoniae R6

40.135

94.577

0.38
  stkP Streptococcus pneumoniae Rx1

39.966

94.577

0.378

Multiple sequence alignment