Detailed information NTG0165029

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS11027_RS06780
• Genome accession: NZ_CP013838
• Coordinates: 1372834..1373559 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain MGAS11027
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1367834..1378559

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS11027_RS06745 (MGAS11027_1379)	rnpM	1367868..1368164 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
MGAS11027_RS06750 (MGAS11027_1380)	nusA	1368180..1369337 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
MGAS11027_RS06755 (MGAS11027_1381)	rimP	1369512..1370048 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
MGAS11027_RS06765 (MGAS11027_1383)	trmB	1370307..1370942 (-)	636	WP_031488472.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS11027_RS06770 (MGAS11027_1384)	ccrZ	1370942..1371733 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS11027_RS06775 (MGAS11027_1385)	-	1371797..1372831 (-)	1035	WP_031577431.1	ABC transporter permease	-
MGAS11027_RS06780 (MGAS11027_1386)	pptA	1372834..1373559 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS11027_RS06785 (MGAS11027_1387)	-	1373631..1374050 (+)	420	WP_002983376.1	HIT family protein	-
MGAS11027_RS06790 (MGAS11027_1388)	-	1374047..1374403 (+)	357	WP_031488470.1	hypothetical protein	-
MGAS11027_RS06795 (MGAS11027_1389)	brpA	1374514..1375797 (-)	1284	WP_031488469.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS11027_RS06800 (MGAS11027_1390)	-	1375806..1376330 (-)	525	WP_031488468.1	GNAT family N-acetyltransferase	-
MGAS11027_RS06805 (MGAS11027_1391)	tsaE	1376305..1376766 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS11027_RS06810 (MGAS11027_1392)	-	1376920..1378380 (-)	1461	WP_031488467.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=165029 MGAS11027_RS06780 WP_002983379.1 1372834..1373559(-) (pptA) [Streptococcus pyogenes strain MGAS11027]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=165029 MGAS11027_RS06780 WP_002983379.1 1372834..1373559(-) (pptA) [Streptococcus pyogenes strain MGAS11027]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714