Detailed information NTG0142222

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: bslm_RS17415
• Genome accession: NZ_CP011101
• Coordinates: 3495950..3497107 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus sp. LM 4-2
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3490950..3502107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
bslm_RS17385 (BsLM_3553)	-	3491203..3491622 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
bslm_RS17390 (BsLM_3554)	comFC	3491696..3492418 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
bslm_RS17395 (BsLM_3555)	comFB	3492382..3492678 (-)	297	WP_003227989.1	late competence protein ComFB	-
bslm_RS17400 (BsLM_3556)	comFA	3492738..3494129 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
bslm_RS17405 (BsLM_3557)	-	3494235..3495080 (-)	846	WP_003244125.1	DegV family protein	-
bslm_RS17410 (BsLM_3558)	degU	3495178..3495867 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
bslm_RS17415 (BsLM_3559)	degS	3495950..3497107 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
bslm_RS17420 (BsLM_3560)	-	3497324..3497977 (+)	654	WP_003227979.1	YigZ family protein	-
bslm_RS17425 (BsLM_3561)	tagV	3497977..3499152 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
bslm_RS17430 (BsLM_3562)	-	3499225..3500301 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
bslm_RS17435 (BsLM_3563)	-	3500446..3501639 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=142222 bslm_RS17415 WP_003227983.1 3495950..3497107(-) (degS) [Bacillus sp. LM 4-2]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=142222 bslm_RS17415 WP_003227983.1 3495950..3497107(-) (degS) [Bacillus sp. LM 4-2]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1