Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ACT74_RS08660 Genome accession   NZ_CP012958
Coordinates   1803134..1803778 (-) Length   214 a.a.
NCBI ID   WP_005544961.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain VT1169     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1798134..1808778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACT74_RS08650 (ACT74_08650) - 1800691..1801536 (+) 846 WP_005544967.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  ACT74_RS08655 (ACT74_08655) gorA 1801631..1803001 (+) 1371 WP_005544964.1 glutathione-disulfide reductase -
  ACT74_RS08660 (ACT74_08660) crp 1803134..1803778 (-) 645 WP_005544961.1 cAMP-activated global transcriptional regulator CRP Regulator
  ACT74_RS08665 (ACT74_08665) - 1803816..1804034 (-) 219 WP_005540236.1 YheU family protein -
  ACT74_RS08670 (ACT74_08670) slmA 1804058..1804657 (-) 600 WP_005540234.1 nucleoid occlusion factor SlmA -
  ACT74_RS08675 (ACT74_08675) dut 1804657..1805112 (-) 456 WP_005569502.1 dUTP diphosphatase -
  ACT74_RS08680 (ACT74_08680) coaBC 1805181..1806380 (-) 1200 WP_005566808.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  ACT74_RS08685 (ACT74_08685) radC 1806558..1807217 (+) 660 WP_005544952.1 RadC family protein Machinery gene
  ACT74_RS08690 (ACT74_08690) rpmB 1807426..1807662 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  ACT74_RS08695 (ACT74_08695) rpmG 1807674..1807844 (+) 171 WP_005544948.1 50S ribosomal protein L33 -
  ACT74_RS08700 (ACT74_08700) mutM 1807926..1808741 (+) 816 WP_005544946.1 bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24231.86 Da        Isoelectric Point: 7.3987

>NTDB_id=137702 ACT74_RS08660 WP_005544961.1 1803134..1803778(-) (crp) [Aggregatibacter actinomycetemcomitans strain VT1169]
MQEQNAQATQSMDPTLEWFLSHCHIHKYPSKSTLINAGEKAETLYYLIQGSVSVLVKDEDGKEMILTYLSQGDFFGEAGL
FEEGQRRSAWIKAKSSCEVAEISYRKFRQLIQVNPEILMYLTAQLAYRLQNTSRQVSNLAFLDVTGRIAQTLLNLAKMPE
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=137702 ACT74_RS08660 WP_005544961.1 1803134..1803778(-) (crp) [Aggregatibacter actinomycetemcomitans strain VT1169]
GTGCAGGAACAAAACGCACAAGCTACGCAATCAATGGATCCGACACTTGAGTGGTTTTTATCCCACTGCCACATCCATAA
ATATCCGTCTAAAAGCACATTAATCAACGCCGGCGAAAAAGCCGAGACACTTTATTATTTAATTCAAGGCTCCGTGTCCG
TTTTGGTCAAAGATGAAGACGGCAAAGAAATGATCCTCACCTATTTAAGCCAAGGGGATTTTTTCGGCGAAGCGGGCTTA
TTTGAAGAAGGACAACGCCGTTCTGCGTGGATTAAAGCAAAATCCTCCTGCGAAGTGGCGGAAATTTCTTATCGTAAATT
TCGCCAGCTGATTCAAGTCAACCCTGAAATCCTGATGTATCTTACTGCCCAATTAGCGTATCGGTTACAAAACACTTCGC
GCCAAGTAAGTAATTTAGCCTTTTTAGATGTCACCGGTCGCATTGCGCAAACCTTGCTCAATCTGGCAAAAATGCCGGAA
GCGATGACTCACCCGGACGGTATGCAAATTAAAATCACCCGCCAGGAAATCGGACAAATGGTCGGTTGTTCGCGGGAAAC
CGTCGGGCGTATTCTGAAAATGCTGGAAGATCAACACCTCATCTCGGCACACGGCAAAACCATCGTAGTTTACGGCACCC
GCTAA

Domains

Predicted by InterProScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-210)

Cyclic nucleotide-binding domain (cNMP_binding)

(27-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

79.808

97.196

0.776
  crp Vibrio cholerae strain A1552

82.178

94.393

0.776
  crp Acinetobacter baumannii D1279779

45.498

98.598

0.449