Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   APQ97_RS11105 Genome accession   NZ_CP012911
Coordinates   2209080..2209721 (-) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain NSUI060     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2204080..2214721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ97_RS11085 (APQ97_11080) - 2204917..2206074 (+) 1158 WP_061286175.1 site-specific integrase -
  APQ97_RS11090 (APQ97_11085) cysK 2206304..2207230 (+) 927 WP_002937015.1 cysteine synthase A -
  APQ97_RS11095 (APQ97_11090) - 2207257..2207628 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  APQ97_RS11100 (APQ97_11095) - 2207630..2209030 (-) 1401 WP_002937018.1 Cof-type HAD-IIB family hydrolase -
  APQ97_RS11105 (APQ97_11100) vraR 2209080..2209721 (-) 642 WP_002937025.1 response regulator transcription factor Regulator
  APQ97_RS11110 (APQ97_11105) - 2209693..2210709 (-) 1017 WP_002937028.1 sensor histidine kinase -
  APQ97_RS11115 (APQ97_11110) liaF 2210706..2211365 (-) 660 WP_225585639.1 cell wall-active antibiotics response protein LiaF -
  APQ97_RS11120 (APQ97_11115) - 2211806..2213095 (-) 1290 WP_002937360.1 IS4-like element ISSsu2 family transposase -
  APQ97_RS11125 (APQ97_11120) - 2213161..2213349 (-) 189 WP_053866409.1 hypothetical protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=137449 APQ97_RS11105 WP_002937025.1 2209080..2209721(-) (vraR) [Streptococcus suis strain NSUI060]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=137449 APQ97_RS11105 WP_002937025.1 2209080..2209721(-) (vraR) [Streptococcus suis strain NSUI060]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCTAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCCGCTATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCTTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413

Multiple sequence alignment