Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   HUO_RS10245 Genome accession   NZ_CP009907
Coordinates   2001479..2003275 (+) Length   598 a.a.
NCBI ID   WP_003630171.1    Uniprot ID   A0AAV4E6A7
Organism   Lactobacillus helveticus strain KLDS1.8701     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2004101..2004577 2001479..2003275 flank 826


Gene organization within MGE regions


Location: 2001479..2004577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUO_RS10245 (HUO_10260) pepF 2001479..2003275 (+) 1797 WP_003630171.1 oligoendopeptidase F Regulator
  HUO_RS12555 - 2003729..2003857 (+) 129 WP_023190901.1 Fic family protein -
  HUO_RS10255 (HUO_10270) - 2004206..2004577 (+) 372 Protein_2031 transposase -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68082.14 Da        Isoelectric Point: 4.9296

>NTDB_id=132871 HUO_RS10245 WP_003630171.1 2001479..2003275(+) (pepF) [Lactobacillus helveticus strain KLDS1.8701]
MAIPTRSEVPEDLKWDLTRIFKTDQDWENAFDKAKDDVAKLSELKGSLAKSGKDLYEGLTKILAVKRDVENIYVYATMSS
DVDTSNSHYLGYVSRVQSLSNQFEAATSFINPEILSIPAEKFEQFKKDEPRLADYAHYLEMITNKRPHTLPAEEEKIIAD
AGDAMSVSENTFNVLTNSDMEYGYVQDEDGNMEQLSNGLYSLLIQSQNRDVRKGAFNTLYASYGQFQNSLASTLSGVVKK
HNYNARMHKYDSAREAALADNGVPVEVYDTLIKEVDSHLDLLHRYVALRKKILGLKDLQMWDMYVPLTGKPALSYNFEEA
KKVAKEAMKPLGEDYLKHVDYIFNNRVIDPVESKGKVTGAYSGGAYDTDPYELLNWEDNIDSLYTLVHETGHSVHSWYTR
HSQPYIYGNYPIFVAEIASTTNENILTEYFLDHITDPKTRAFILNHYLDSFKGTLFRQTQFAVFEQFIHEADAKGEPLTA
DILNDVYGQINQHYYGDSVEPGGDIALEWSRIPHFYYNFYVYQYATGFAAATALANKVVHGSQADRDAYLGYLKSGSSDY
PTEIMKRAGVDMTKPDYLKDAFKTFEKRLNEFESLIGK

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=132871 HUO_RS10245 WP_003630171.1 2001479..2003275(+) (pepF) [Lactobacillus helveticus strain KLDS1.8701]
ATGGCGATTCCAACAAGAAGCGAAGTCCCAGAAGATTTGAAGTGGGATTTAACCCGCATCTTTAAAACAGACCAAGACTG
GGAAAATGCCTTTGACAAGGCAAAAGATGACGTGGCTAAGCTAAGTGAATTAAAGGGAAGCTTGGCTAAATCAGGCAAAG
ATTTGTATGAAGGCTTGACCAAGATTTTGGCAGTTAAACGTGATGTAGAAAATATTTACGTTTATGCCACTATGTCTAGC
GATGTTGATACTTCTAACTCACATTATTTGGGCTACGTTAGCCGCGTGCAAAGCTTGTCCAATCAATTTGAAGCAGCAAC
CAGTTTTATTAATCCTGAAATTTTGAGTATCCCTGCCGAAAAGTTTGAACAATTCAAAAAAGACGAGCCAAGATTAGCTG
ATTACGCCCACTATTTGGAAATGATCACTAACAAGCGTCCTCATACTTTACCAGCAGAAGAAGAAAAAATTATCGCTGAC
GCAGGGGATGCCATGAGCGTGTCAGAGAATACCTTTAACGTTTTAACCAACTCTGACATGGAATATGGTTATGTGCAAGA
TGAAGACGGCAACATGGAGCAATTATCCAATGGCTTGTATTCATTATTGATTCAGTCCCAAAATCGTGACGTGCGTAAAG
GTGCTTTTAATACTCTCTATGCCAGCTATGGTCAATTCCAAAACTCGCTTGCCTCTACTCTCTCCGGCGTTGTGAAAAAA
CATAACTACAACGCACGCATGCACAAGTATGATTCAGCTCGTGAAGCCGCATTAGCTGATAACGGCGTACCTGTTGAAGT
TTACGACACATTAATTAAAGAAGTTGATTCACACCTTGACTTGCTTCACCGTTATGTCGCATTGCGCAAGAAAATTTTAG
GTCTTAAAGACTTACAAATGTGGGACATGTACGTGCCGCTAACTGGTAAGCCTGCTTTGTCTTACAACTTTGAAGAGGCT
AAAAAGGTAGCTAAAGAAGCCATGAAGCCACTTGGCGAAGACTACTTAAAGCATGTTGATTATATTTTTAACAACCGTGT
GATTGACCCTGTTGAATCTAAGGGCAAGGTTACTGGTGCTTACTCTGGTGGTGCTTACGATACCGATCCATATGAACTTT
TGAACTGGGAAGACAATATCGATTCACTCTATACTTTAGTTCATGAAACTGGACACTCAGTTCACTCTTGGTACACCCGC
CACAGTCAGCCTTATATCTATGGTAATTACCCAATCTTCGTGGCTGAAATTGCTTCAACCACTAATGAAAATATTTTGAC
TGAATATTTCTTGGACCATATTACTGATCCTAAGACGCGCGCATTCATCTTGAACCACTACCTTGATTCATTCAAGGGTA
CATTGTTCCGCCAAACTCAATTTGCGGTATTTGAACAATTTATCCACGAAGCAGATGCTAAGGGCGAACCATTGACTGCC
GATATTTTGAATGATGTTTATGGTCAAATTAACCAGCATTACTACGGCGACAGTGTTGAACCTGGTGGCGATATTGCGCT
TGAATGGTCACGAATTCCGCACTTCTACTACAACTTCTACGTTTATCAATATGCGACTGGATTTGCGGCTGCAACGGCTT
TGGCTAACAAGGTTGTGCATGGTAGTCAGGCTGATAGGGATGCATACCTGGGCTACCTTAAGTCAGGTTCTAGTGACTAT
CCTACTGAGATCATGAAGCGTGCCGGCGTTGACATGACTAAGCCCGATTATTTGAAAGATGCTTTCAAGACTTTTGAAAA
GAGATTGAACGAATTCGAGAGTTTGATTGGTAAGTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(113-181)

Peptidase family M3 (Peptidase_M3)

(203-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.515

99.331

0.512

Multiple sequence alignment