Detailed information NTG0124457

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: VAA049_RS16690
• Genome accession: NZ_CP010811
• Coordinates: 3622791..3625613 (+)
• Length: 940 a.a.
• NCBI ID: WP_000357696.1
• Uniprot ID: Q9KUW5
• Organism: Vibrio cholerae strain 1154-74
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3617791..3630613

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VAA049_RS16670 (VAA049_3278)	csrD	3617982..3619994 (-)	2013	WP_046122270.1	RNase E specificity factor CsrD	-
VAA049_RS16675 (VAA049_3279)	ssb	3620118..3620654 (-)	537	WP_001887866.1	single-stranded DNA-binding protein	Machinery gene
VAA049_RS16680 (VAA049_3280)	qstR	3620946..3621590 (+)	645	WP_046122271.1	LuxR C-terminal-related transcriptional regulator	Regulator
VAA049_RS16685 (VAA049_3281)	galU	3621763..3622635 (+)	873	WP_001920788.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
VAA049_RS16690 (VAA049_3282)	uvrA	3622791..3625613 (+)	2823	WP_000357696.1	excinuclease ABC subunit UvrA	Machinery gene
VAA049_RS16695 (VAA049_3283)	-	3625678..3627462 (+)	1785	WP_046122272.1	oligosaccharyltransferase	-
VAA049_RS16700 (VAA049_3284)	-	3627541..3628659 (-)	1119	WP_046122273.1	alanine--glyoxylate aminotransferase family protein	-
VAA049_RS16705 (VAA049_3285)	lysC	3629123..3630478 (+)	1356	WP_046122274.1	lysine-sensitive aspartokinase 3	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 104327.86 Da
• Isoelectric Point: 6.4814

>NTDB_id=124457 VAA049_RS16690 WP_000357696.1 3622791..3625613(+) (uvrA) [Vibrio cholerae strain 1154-74]
MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKG
EHVKTLENLAAQGFIRARIDGETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD
GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLSLAQGAIRGWDQKNFYYFQML
TALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYINDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYI
SNKPCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS
RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIG
PGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVPEQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGV
SGSGKSTLINDTFFKIAHTALNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES
RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTVEDAREFFD
PVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDH
GNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN

Nucleotide

• Length: 2823 bp

>NTDB_id=124457 VAA049_RS16690 WP_000357696.1 3622791..3625613(+) (uvrA) [Vibrio cholerae strain 1154-74]
ATGGACAAAATCGAAGTACGCGGCGCTCGTACCCATAACCTCAAAAATATCAATCTGACCATTCCTCGTGACAAATTGAT
TGTCATCACCGGCCTCTCTGGTTCAGGTAAATCCTCACTGGCTTTTGATACGCTGTACGCAGAAGGTCAACGGCGTTATG
TCGAATCACTCTCGGCTTATGCGCGCCAATTCCTTTCTCTGATGGAAAAGCCGGATGTAGACCATATTGAGGGGCTTTCA
CCCGCGATTTCGATTGAGCAGAAGTCCACTTCCCATAACCCACGCTCTACTGTGGGTACAATTACGGAAGTATATGACTA
TTTACGTCTACTCTACGCTCGGGTTGGTGAGCCACGCTGTCCCGAACACCAAGTGCCACTGAAAGCGCAAACCATCAGTC
AGATGGTAGACAAAGTACTGGAATTGCCAGAAGGCAGCAAAATGATGCTGCTGGCAACCATAGTCAAAGAGCGCAAAGGC
GAACACGTTAAAACATTGGAAAACCTTGCTGCGCAGGGCTTTATTCGTGCGCGTATCGATGGTGAAACCTGCGATCTGAC
CGATCCACCGAAACTCGAACTGCACAAAAAGCATACCATTGAAGTAATTGTCGACCGTTTCAAAGTGCGCAGTGATCTGC
AGCAACGCTTAGCCGAATCCTTTGAAACCGCCTTAGAACTTTCTGGCGGTATCGTCGTTGTCGCACCGATGGAAGGCGAT
GGCGAAGAGCAGATTTTCTCGGCTAACTTTGCTTGTCCACATTGCGGTTACAGCATGCGCGAGCTTGAACCACGCCTGTT
CTCCTTCAACAACCCAGCCGGTGCTTGTCCAACCTGTGATGGTTTAGGAGTACAGCAGTATTTCGATCCAGATCGAGTGA
TTCAAGATGCCAATTTAAGTTTGGCACAAGGCGCAATCCGCGGTTGGGATCAAAAGAACTTTTATTATTTCCAGATGCTG
ACTGCACTGGCCGAGCACTACGATTTTGATGTACACACGCCCTTCAATAAGCTGAGCAAAAAGATTCAGGAAATCATTCT
GCACGGCTCTGGTCGCACCGAAATTGAATTTAAGTACATCAATGATCGGGGTGATATTCGCCTTAAAAAACATCCTTTTG
AAGGAATTTTGCATAATTTGGAGCGCCGCTATCGCGATACCGAATCCAACTCGGTGCGTGAGGAGCTGGCAAAATACATC
TCCAACAAGCCTTGCAGCAGCTGTGATGGTACGCGCTTAAAAATCGAAGCACGCAATGTGTTTATTAATGATACTGCGCT
GCCAACGATTGTAGAACTGAGCATTGCTGATGCGCTAACGTTCTTCCAAGAGCTCAAACTGGAAGGCCAACGTGCACAAA
TCGCTGAAAAAGTGATGAAAGAGATTAATGACCGGCTGCAATTTTTGGTCAATGTCGGGCTCAATTACTTAAATCTCTCG
CGCAGCGCCGAGACGCTTTCCGGTGGCGAAGCTCAGCGCATTCGCCTAGCCAGTCAGATTGGTGCCGGTTTAGTCGGTGT
AATGTATGTCCTTGATGAACCCTCGATTGGCCTCCACCAACGCGACAACGAACGCTTGCTGCAAACCCTCACCCACTTAC
GCAATCTAGGGAATACCGTGTTAGTGGTTGAGCATGATGAAGATGCGATTCGCATGGCAGATCATGTGATTGATATTGGC
CCAGGTGCTGGCGTACACGGCGGCATGGTGGTTGCCGAAGGCAATGTGGAGGAAATCATCGCCAATCCAAACTCACTCAC
AGGTCAATATCTCAGTGGCGTGAAAAAAATTGCGGTACCAGAGCAGCGCACACCAAAAGATGCGAAGAAAACGGTAGAGC
TTAAAGGCGCGGTCGGTAATAACTTAAAAAATGTTGACCTGTCTATTCCTGTTGGCCTGTTTACTTGTGTGACGGGCGTT
TCAGGTTCGGGAAAATCCACTCTGATCAACGATACCTTCTTTAAGATTGCCCATACCGCACTCAATGGCGCGACGACGGC
AACACCTGCGCCTTATCGCTCCATTCAAGGTCTAGAACACTTTGATAAAGTGATCGATATCGATCAGAGCCCAATTGGTC
GCACTCCTCGCTCCAATCCTGCCACTTACACCGGAATCTTCACTCCAATCCGTGAATTGTTTGCCGGAACACAAGAGTCT
CGCTCGCGTGGTTATCAGCCGGGACGCTTTAGTTTCAACGTGCGCGGAGGGCGCTGTGAAGCGTGCCAAGGCGATGGCGT
GATCAAAGTTGAAATGCACTTCTTACCCGATGTGTATGTGCCTTGTGATGTGTGTAAAGGTAAGCGCTATAACCGAGAAA
CCTTGGAAGTGCGCTACAAAGGCAAGACGATTGATGAAGTTTTGGACATGACCGTTGAAGACGCACGCGAGTTTTTTGAC
CCCGTACCTGTGATAGCACGTAAGCTGCAAACCTTGATGGATGTTGGGTTGTCCTACATTCGACTAGGGCAATCAGCCAC
TACTCTATCAGGAGGTGAAGCGCAGCGGGTAAAATTAGCGCGTGAACTCTCCAAACGAGATACGGGCAAAACCCTGTATA
TTTTGGATGAACCAACCACGGGCCTACACTTCCACGATATTCAGCAACTATTGAGCGTTCTGCACCGCTTGCGTGACCAT
GGCAATACCGTGGTGGTGATTGAGCATAACTTGGATGTGATCAAAACGGCTGACTGGATCATCGATTTAGGCCCCGAAGG
CGGCCAAGGCGGCGGACTGATTATTGCAGAAGGAACACCAGAAGATGTGGCGCAGATCGAAGCTTCACATACCGCACGTT
TCCTCAAGCCTTTGTTGAATTAG

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (130-236)

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-398)

• ABC transporter (ABC_tran) (622-859)

3D structure

• AlphaFold DB: Q9KUW5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.9	100	0.581
uvrA	Streptococcus pneumoniae TIGR4	57.9	100	0.581
uvrA	Streptococcus pneumoniae D39	57.9	100	0.581